Table 4. Univariate and multivariate analyses.
| Parameters | Univariate analyses | Multivariate analyses | |||
|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | ||
| Age (year) | 0.996 (0.946−1.049) | 0.885 | − | − | |
| Sex | 0.409 (0.161−1.039) | 0.060 | 0.208 (0.021−2.094) | 0.183 | |
| Smoking | 1.955 (0.779−4.910) | 0.153 | − | − | |
| Maximum diameter (mm) | 1.799 (1.210−2.675) | 0.004# | 0.919 (0.344−2.455) | 0.866 | |
| Subtype | 2.143 (0.808−5.683) | 0.126 | − | − | |
| Stage | 1.186 (1.017−1.382) | 0.029# | 0.919 (0.658−1.283) | 0.620 | |
| Grade | 0.453 (0.233−0.880) | 0.020# | 1.701 (0.381−7.590) | 0.486 | |
| ADC (×10−3 mm2/s) | 1.189 (0.222−6.376) | 0.840 | − | − | |
| D (×10−3 mm2/s) | 0.256 (0.108−0.604)& | 0.002# | 0.081 (0.013−0.503)& | 0.007# | |
| D* (×10−3 mm2/s) | 1.002 (0.992−1.012) | 0.727 | − | − | |
| f (%) | 0.957 (0.922−0.993) | 0.018# | 0.997 (0.961−1.035) | 0.894 | |
| MTRasym (3.5 ppm) (%) | 2.080 (1.386−3.121) | <0.001# | 4.550 (1.609−12.863) | 0.004# | |
| SUVmax (g/cm3) | 1.299 (1.136−1.486) | <0.001# | 1.517 (1.079−2.133) | 0.016# | |
| MTV (cm3) | 1.096 (1.037−1.159) | 0.001# | 1.172 (0.953−1.442) | 0.132 | |
| TLG (g) | 1.018 (1.006−1.030) | 0.002# | 0.984 (0.951−1.019) | 0.373 | |
&, OR for per 1 standard deviation; #, indicates the logistic regression analyses with statistical significance. PD-L1, programmed cell death-ligand 1; OR, odds ratio; CI, confidence interval; ADC, apparent diffusion coefficient; D, diffusion coefficient; D*, pseudo diffusion coefficient; f, perfusion fraction; MTRasym (3.5 ppm), magnetization transfer ratio asymmetry at 3.5 ppm; SUVmax, maximum standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis.