Figure 3.

A) Schematic illustration of the therapeutic mechanism of the double‐network hydrogel (¹²⁵I‐GPA) via PTT and brachytherapy for synergistic treatment of the postoperative breast cancer recurrence in infectious wounds. B) Breast cancer recurrence rate of PBS, ¹²⁵I‐GNR, ¹²⁵I‐GPA, and PA hydrogels with or without laser irradiation (n = 6). C) In vivo breast cancer locoregional recurrence curve of PBS, GNR, ¹²⁵I‐GPA and PA hydrogels with or without laser irradiation (n = 6). D) Average body weights of the mice of different groups (n = 6). E) Photographs showing the gross tumor volume after treatment of different groups. F) SPECT images of the breast region before and after injection of ¹²⁵I‐GNR, ¹²⁵I‐GP, and ¹²⁵I‐GPA hydrogels during 4 weeks implantation. Asterisks (**) denoted significant differences (p < 0.01).