Figure. Unadjusted Cumulative Incidence Rates and Adjusted Hazard Ratios (HRs) of Psychological Developmental and Neurosensory Disorders in Children According to Maternal Antenatal Corticosteroid Treatment Exposure.
aNumber of children with diagnosis of psychological developmental and neurosensory disorders and cumulative incidences during follow-up of the entire cohort of children (unadjusted analyses, 670 097; adjusted analyses, 642 158), term-born children (unadjusted analyses, 641 487; adjusted analyses, 615 305), and preterm-born children (unadjusted analyses, 28 610; adjusted analyses, 26 853) eligible for data analyses.
bAbsolute differences may differ from the arithmetic difference of group totals because of rounding.
cFrom χ2 statistics.
dHazard ratios, 95% CIs, and P values are from multivariable Cox proportional hazards regression models adjusted for maternal age at delivery, parity, mode of delivery, maternal smoking during pregnancy, prepregnancy body mass index, premature rupture of membranes (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [ICD-10] code O42), gestational diabetes (ICD-10 code O24), hypertension in pregnancy (ICD-10 codes O10 and O13-O15), and child sex, Apgar score (maximum of 1 and 5 min), admission to neonatal intensive care unit, weight and gestational age at birth. For child psychological developmental disorders, models were adjusted additionally for maternal mental and behavioral disorder diagnoses (ICD-10 codes F00-F99); for child vision and hearing disorders, models were adjusted additionally for maternal eye, adnexa, ear, and mastoid disorder diagnoses (ICD-10 codes H00-H95); and for child epilepsy and cerebral palsy, models were adjusted additionally for maternal nervous system disorder diagnoses (ICD-10 codes G00-G99).