Table 1. Demographics and History.
| No./total No. (%) | P value | ||
|---|---|---|---|
| Intended surgery | Medical management | ||
| No. of patients (%) | 5131 (91.4) | 480 (8.6) | |
| Age | <.001 | ||
| No. of patients | 5130 | 480 | |
| Mean (SD), y | 60.4 (14.1) | 70.9 (14.7) | |
| Gender | |||
| Male | 3442/5131 (67.1) | 252/480 (52.5) | <.001 |
| Female | 1689/5131 (32.9) | 228/480 (47.5) | |
| Race | |||
| Asian | 221/4667 (4.7) | 38/436 (8.7) | <.001 |
| Black | 507/4667 (10.9) | 30/436 (6.9) | .01 |
| White | 3735/4667 (80.0) | 355/436 (81.4) | .49 |
| BMIa | .20 | ||
| No. of patients | 3103 | 200 | |
| Median (IQR) | 27.7 (24.6-31.9) | 27.3 (23.5-32.2) | |
| Patient transferred | 3681/5131 (71.7) | 308/480 (64.2) | <.001 |
| Time from symptom onset to presentation | .85 | ||
| No. of patients | 2517 | 241 | |
| Median (IQR), h | 1.5 (0.8-3.3) | 1.5 (0.8-3.4) | |
| Time from presentation to diagnosis | .005 | ||
| No. of patients | 2697 | 238 | |
| Median (IQR), h | 2.5 (1.2-5.3) | 3.5 (1.4-7.3) | |
| Time from presentation to surgery | |||
| No. of patients | 2893 | ||
| Median (IQR), h | 6.0 (4.0-15.0) | ||
| Time from presentation to death | <.001 | ||
| No. of patients | 470 | 133 | |
| Median (IQR), h | 64.7 (16.2-231.4) | 27.7 (8.4-70.4) | |
| History of hypertension | 3603/4718 (76.4) | 349/446 (78.3) | .37 |
| Diabetes | 416/4342 (9.6) | 68/422 (16.1) | <.001 |
| Marfan syndrome | 166/4294 (3.9) | 17/407 (4.2) | .76 |
| Atherosclerosis | 748/4289 (17.4) | 135/416 (32.5) | <.001 |
| Known aortic aneurysm | 583/4336 (13.4) | 94/424 (22.2) | <.001 |
| Prior aortic dissection | 181/4293 (4.2) | 42/423 (9.9) | <.001 |
| Bicuspid aortic valve | 172/4072 (4.2) | 7/337 (2.1) | .06 |
| Aortic valve disease | 485/4297 (11.3) | 51/408 (12.5) | .46 |
| Other aortic disease | 91/4228 (2.2) | 11/402 (2.7) | .45 |
| Current smoker | 907/2777 (32.7) | 57/240 (23.8) | .005 |
| Family history of aortic disease | 246/2732 (9.0) | 21/209 (10.0) | .61 |
| Peripheral arterial disease | 112/2977 (3.8) | 17/223 (7.6) | .005 |
| COPD | 304/3057 (9.9) | 43/232 (18.5) | <.001 |
| Chronic kidney insufficiency | 218/3036 (7.2) | 29/229 (12.7) | .002 |
| Prior cardiac surgery | 516/4276 (12.1) | 114/424 (26.9) | <.001 |
| Aneurysm/AAD | 223/4226 (5.3) | 63/421 (15.0) | <.001 |
Abbreviations: AAD, acute aortic dissection; BMI, body mass index; COPD, chronic obstructive pulmonary disease.
a
Calculated as weight in kilograms divided by height in meters squared.