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. 2022 Aug 25;21(12):881–898. doi: 10.1038/s41573-022-00542-z

Fig. 1. Timeline of the development of major covalent drugs.

Fig. 1

Each covalent drug is classified according to the drug type or type of disease it treats. Unless otherwise indicated, the date refers to the first approval by the US Food and Drug Administration. NSAID, non-steroidal anti-inflammatory drug.