Table 10.
List of approved drugs associated with the SARS-CoV-2 membrane protein for the treatment of COVID-19.
| Membrane protein | Drugs composition |
|---|---|
| TLR3 | Rintatolimod, Hiltonol, Hydroxychloroquine, Aspirin |
| Azd-8848 | Imiquimod, Resiquimod, Isatoribine, Loxoribine, Hydroxychloroquine |
| TLR7 | Telratolimod, Vesatolimod, Hydroxychloroquine sulfate, Gsk-2245035 |
| TLR9 | Hydroxychloroquine sulfate, Agatolimod sodium, Tilsotolimod, Emd-1201081 |
| MICB | Ribavirin |
| UGT1A1 | Bilirubin, Indinavir, Tranilast, Nilotinib, 7-Ethyl-10-hydroxycamptothecin |
| Dolutegravir, Letermovir, Raltegravir, Raloxifene, Etoposide | |
| PSMC5 | Carfilzomib, Ixazomib, Bortezomib, Ixazomib citrate, Oprozomib |
| PSMD11 | Carfilzomib, Bortezomib, Ixazomib, Oprozomib |
| PSMD14 | Carfilzomib, Bortezomib, Ixazomib citrate, Oprozomib Sulfuretin |
| PSME1 | Carfilzomib,Bortezomib |
| PSMA2 | Carfilzomib, Bortezomib,Ixazomib citrate, Oprozomib, Marizomib |
| PSMB2 | Carfilzomib, Bortezomib,Ixazomib citrate, Oprozomib, Marizomib, KZR-616 |
| MGAT4A | Bevacizumab, Capecitabine, Oxaliplatin, Cetuximab |
| ALDH2 | Prunetin, Acetaldehyde, Diacetylmorphine, Disulfiram |
| CHST3 | Docetaxel, Thalidomide |
| CHST1 | Imatinib |
| KIT | Imatinib, Quizartinib, Nilotinib, Sunitinib, Amuvatinib |
| GGT1 | Cannabinol, Ditiocarb, Mannitol, Aminoglutethimide, Mestranol |
| VCAM1 | Tamoxifen, Piroxicam, Dexamethasone, Liothyronine Sodium |
| Mercaptopurine, Dexamethasone, Troglitazone, Cyclosporine | |
| CTLA4 | Tremelimumab, Ipilimumab, Zalifrelimab, Abatacept, Atezolizumab, |
| Sirolimus, Wortmannin, Dexamethasone, Methimazole, Antibiotic | |
| LDLR | Cholestyramine, Evolocumab, Mipomersen, Tributyrin, Alirocumab |
| Acetylcysteine, Gemfibrozil, Corticotropin, Retinol | |
| SDC1 | Indatuximab Ravtansine, Heparin |
| BCL2 | Docetaxel, Paclitaxel, Hypoxanthine, Navitoclax |
| Oblimersen, Venetoclax, Obatoclax, Beauvericin, Isosorbide, Protuboxepin A | |
| FOLH1 | Capromab, Technetium TC-99 m Trofolastat Chloride, Mipsagargin, MDX-070 |
| MLN-2704, MLN-591RL,Androstanolone, Methotrexate, Docetaxel, Mercaptopurine | |
| FMO3 | Itopride, Tamoxifen, Nicotine, Rosuvastatin, Tacrolimus |
| FMO1 | Tamoxifen, Nicotine, Olanzapine |
| COL18A1 | Glutamine, Tamoxifen, Aspirin, Collagenase clostridium histolyticum |
| Thrombin, Celecoxib, Ocriplasmin | |
| ERBB3 | Afatinib, Seribantumab, Patritumab,Cetuximab, Lapatinib |
| Pertuzumab, Panitumumab, Erlotinib, Aspirin, Alteplase | |
| ERBB2 | Lapatinib, Afatinib, Trastuzumab, Pertuzumab, Dacomitinib |
| AC-480, Margetuximab, Tucatinib, MM-111, Sapitinib | |
| NRG1 | Afatinib, Seribantumab, Patritumab, Cetuximab, Lapatinib |
| Pertuzumab, Panitumumab, Erlotinib, Aspirin, Alteplase | |
| CD38 | Daratumumab, Isatuximab, Thrombin |
| LEPR | Metreleptin, Atorvastatin, Simvastatin |