Table 3.
Details of identified positive casesa.
| Patient ID | Area | Collection date | Delayb | Age (yr.) | Sex | RT PCR | NsP3c | RdRpc | Spike Ac | Spike Bc | IgMd | IgAd | IgGd | PRNT 80%e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-pandemic cases | ||||||||||||||
| 1 | Milan | 12/09/2019 | 3 | 0.67 | M | – | – | – | – | + (U) | + | - | + | – |
| 2 | East Milan | 12/10/2019 | 0 | 18 | F | – | – | – | – | + (S) | – | – | – | – |
| 3 | Brescia | 17/10/2019 | 1 | 9 | F | – | – | + (U) | – | – | – | – | – | – |
| 4 | North-West Milan | 19/10/2019 | 1 | 1 | M | – | – | + (S) | – | – | – | + | + | – |
| 5 | Brescia | 22/10/2019 | 1 | 1 | F | – | + (S) | – | – | – | + | – | – | -f |
| 6 | East Milan | 23/10/2019 | NA | 1 | F | – | – | + (S) | – | – | + | – | – | – |
| 7 | North-West Milan | 22/11/2019 | 7 | 2 | M | – | + (S) | – | – | – | NA | NA | NA | NA |
| 8 | West Milan | 05/12/2019 | 4 | 4 | M | – | – | – | – | + (S) | NA | NA | NA | NA |
| 9 | South-East Milan | 15/12/2019 | 2 | 25 | F | - | - | + (U) | + (U) | + (U) | – | – | – | – |
| 10 | Milan | 09/01/2020 | 1 | 53 | M | – | – | – | – | + (U) | – | – | – | – |
| 11 | Brescia | 14/01/2020 | 4 | 40 | M | – | – | – | – | + (S) | – | – | – | NA |
| Pandemic cases | ||||||||||||||
| 12 | North-West Milan | 15/01/2021 | 1 | 65 | F | – | – | – | – | – | – | + | + | 1:60 |
| 13 | Lodi | 16/01/2021 | 9 | 32 | F | – | + (U) | – | + (U) | – | + | - | - | – |
| 14 | North Milan | 25/01/2021 | 4 | 1 | F | – | – | – | – | – | + | + | + | 1:160 |
| 15 | Milan | 26/02/2021 | 5 | 47 | M | – | – | – | – | + (U) | - | - | - | – |
a
Only patients that tested positive in PCR or that presented neutralizing antibodies are included.
b
Days from exanthema onset to sample collection.
c
U: urine sample was positive,S: oropharyngeal swab was positive.
d
NA: serum/data not available.
e
PRNT: plaque-reduction neutralization test.
f
This serum caused 62% plaque reduction at a 1:10 dilution.