TABLE 3.
Multinomial logistic regression model investigating the association between nighttime fasting and time of breakfast with breast cancer risk subtype.
| Controls | HER2 + |
+ Hormonal receptors |
Triple-negative |
||||
| Mean (SD) or N (%) |
Mean (SD) or N (%) |
RR (95% CI)a |
Mean (SD) or N (%) |
RR (95% CI)a |
Mean (SD) or N (%) |
RR (95% CI)a |
|
| All women | |||||||
| Nighttime fasting (hours) | 11.0 (1.6) | 11.5 (1.6) | 1.13 (0.96–1.34) | 11.0 (1.6) | 0.98 (0.89–1.08) | 10.9 (1.6) | 0.96 (0.75–1.22) |
| Time of breakfast | 8.4 (1.4) | 8.8 (1.6) | 1.07 (0.89–1.28) | 8.5 (1.3) | 1.04 (0.93–1.17) | 8.4 (1.4) | 1.01 (0.75–1.35) |
| Total | 1,232 (54.8) | 200 (8.9) | 740 (32.9) | 75 (3.3) | |||
| Premenopausal women | |||||||
| Nighttime fasting (hours) | 10.6 (1.5) | 11.5 (1.8) | 1.09 (0.84–1.41) | 10.8 (1.7) | 0.94 (0.81–1.10) | 10.7 (1.6) | 0.93 (0.63–1.37) |
| Time of breakfast | 8.2 (1.3) | 9.1 (1.8) | 1.38 (1.03–1.85) | 8.5 (1.4) | 1.19 (0.99–1.42) | 8.5 (1.5) | 1.11 (0.69–1.78) |
| Total | 380 (49.5) | 71 (9.3) | 290 (37.8) | 26 (3.4) | |||
| Postmenopausal women | |||||||
| Nighttime fasting (hours) | 11.2 (1.7) | 11.4 (1.5) | 1.19 (0.95–1.48) | 11.2 (1.5) | 1.02 (0.89–1.16) | 11.0 (1.6) | 1.02 (0.74–1.41) |
| Time of breakfast | 8.5 (1.5) | 8.7 (1.5) | 0.92 (0.72–1.18) | 8.5 (1.2) | 0.98 (0.84–1.14) | 8.4 (1.4) | 0.91 (0.62–1.32) |
| Total | 852 (57.6) | 129 (8.7) | 450 (30.4) | 49 (3.3) | |||
aModels were adjusted for age, center, educational status, family history of breast cancer, menarche, number of children, BMI, contraceptive use, hormonal replacement therapy, menopausal status, breastfeeding, and age of the first child. Models were mutually adjusted for both exposures. Controls were considered as the reference group.
N, sample size; RR, relative Risk; SD, standard deviation.