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. Author manuscript; available in PMC: 2023 Jul 13.
Published in final edited form as: Nature. 2022 Jul 13;607(7920):816–822. doi: 10.1038/s41586-022-04952-2

Extended Data Fig. 5. cryo-EM map of structural elements of WNT3Ap/LGK974-bound PORCN and pamWNT3Ap-bound PORCN.

Extended Data Fig. 5

a, The Fourier shell correlation (FSC) curves calculated between the refined structure model and the half map used for refinement (yellow), the other half map (gray) and the full map (blue) of WNT3Ap/LGK974-bound PORCN. b, Density map colored by local resolution estimation using cryoSPARC. c, The major helices of PORCN, WNT3Ap and LGK974. d, The Fourier shell correlation (FSC) curves calculated between the refined structure model and the half map used for refinement (yellow), the other half map (gray) and the full map (blue) of pamWNT3Ap-bound PORCN. e, Density map colored by local resolution estimation using cryoSPARC. f, The major helices of PORCN and pamWNT3Ap.