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. Author manuscript; available in PMC: 2023 Jul 13.
Published in final edited form as: Nature. 2022 Jul 13;607(7920):816–822. doi: 10.1038/s41586-022-04952-2

Extended Data Fig. 9. The structure of HHAT-SHH-N complex.

Extended Data Fig. 9

a, Representative Superose 6 increase 10/300 GL gel-filtration chromatogram of HHAT-SHH-N complex with Fab3H02. The peak fraction is shown on SDS-PAGE with molecular markers. Each protein is indicated. For gel source data, see Supplementary Fig. 1b. b, Fourier shell correlation (FSC) curve as a function of resolution using RELION-3 output. c, Cryo-EM map of the complex after 3D refinement reveals the mean body of SHH-N protein at the threshold level of 0.003 but not 0.01.