Table 1.
Baseline characteristics, features, and outcomes
| Characteristic* | Accelerated, N = 1465 |
Standard, N = 1462 |
|---|---|---|
| Age, mean (SD) | 64 (14) | 64 (13) |
| Sex, n (%) | ||
| Female | 470 (32) | 467 (32) |
| Male | 995 (68) | 995 (68) |
| Sepsis, n (%) | 855 (58) | 834 (57) |
| Surgical admission, n (%) | 492 (34) | 473 (32) |
| Mechanical ventilation, n (%) | 1103 (75) | 1148 (79) |
| Creatinine, mean (SD) | 121 (92) | 118 (87) |
| Chronic kidney disease, n (%) | 658 (45) | 626 (43) |
| SOFA score, median (IQR) | 12 (9–14) | 12 (9–14) |
| SAPS II score, median (IQR) | 57 (45–71) | 59 (47–73) |
| Received KRT, n (%) | 1418 (97) | 903 (62) |
| Time until KRT, hours, median (IQR) | 4 (3–7) | 29 (17–68) |
| Did not receive KRT | 48 | 559 |
| Outcomes | ||
| 90-day mortality n (%) | 643 (44) | 639 (44) |
| KRT dependency at 90 days, n (%) | 85 (10) | 49 (6) |
| KRT dependency or death at 90 days, n (%) | 728 (50) | 688 (47) |
| Death in hospital, n (%) | 643 (44) | 639 (44) |
| Rehospitalization at 90 days, n (%) | ||
| No | 653 (45) | 685 (47) |
| Yes | 166 (11) | 138 (9) |
| Days alive and hospital-free at 90 days, medial (IQR) | 10 (0, 65) | 9 (0, 64) |
| Days alive and KRT-free at 90 days, median (IQR) | 50 (0, 87) | 64 (0, 90) |
*Missing values not shown in table