Table 2.
Metabolic rate and carbohydrate oxidation during the 3-h oral glucose tolerance test
| Experiment II | Sedentary control | SPU1 | SPU2 | p-value |
||
|---|---|---|---|---|---|---|
| SED vs SPU1 | SED vs SPU2 | SPU1 vs SPU2 | ||||
| METs | 0.86 ± 0.05 | 1.31 ± 0.07 | 1.69 ± 0.12 | 5 × 10−8 | 3 × 10−6 | 9 × 10−6 |
| AEE (Δ kcal/min) | --- | 0.60 ± 0.05 | 1.12 ± 0.11 | 2 × 10−8 | 3 × 10−6 | 4 × 10−6 |
| Energy exp. (kcal/3 h) | 207 ± 11 | 315 ± 16 | 402 ± 24 | 2 × 10−8 | 4 × 10−6 | 8 × 10−6 |
| Total AEE (Δ kcal/3 h) | --- | 108 ± 9 (+36 kcal/h) | 201 ± 19 (+67 kcal/h) | 2 × 10−8 | 3 × 10−6 | 4 × 10−6 |
| RER (VCO2/VO2) | 0.84 ± 0.02 | 0.88 ± 0.01 | 0.90 ± 0.02 | 0.019 | 0.003 | 0.112 |
| Total carbohydrate oxidation (mg/min) | 135 ± 18 | 276 ± 14 | 392 ± 25 | 1 × 10−6 | 4 × 10−6 | 0.0002 |
| Δ mg/min above control | --- | 141 ± 16 | 253 ± 26 | 1 × 10−6 | 5 × 10−6 | 0.0002 |
| Total in 3 h (g) | 24.2 ± 3.2 | 49.7 ± 2.5 | 70.6 ± 4.6 | 1 × 10−6 | 4 × 10−6 | 0.0002 |
| Δ above control (g) | --- | 25.5 ± 2.9 (2.1 fold) | 45.5 ± 4.6 (2.9 fold) | 1 × 10−6 | 5 × 10−6 | 0.0002 |
| Soleus carbohydrate oxidation (Δ mg/min) | --- | 113 ± 13 | 202 ± 21 | 1 × 10−6 | 5 × 10−6 | 0.0002 |
Mean ± SEM. Metabolic rate and carbohydrate oxidation during the postprandial period following the ingestion of 75 g glucose. Each individual performed a sedentary control and one or both of the levels of local contractile activity. The delta (Δ) is the difference between sedentary control and activity. Differences between conditions were determined by a mixed effects model followed by Tukey’s multiple comparison tests. N = 15 for SPU1 effects and N = 10 for SPU2. See also Experiment II results in Figure S1 and Table S2.