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. 2022 Aug 5;25(9):104869. doi: 10.1016/j.isci.2022.104869

Table 2.

Metabolic rate and carbohydrate oxidation during the 3-h oral glucose tolerance test

Experiment II Sedentary control SPU1 SPU2 p-value
SED vs SPU1 SED vs SPU2 SPU1 vs SPU2
METs 0.86 ± 0.05 1.31 ± 0.07 1.69 ± 0.12 5 × 10−8 3 × 10−6 9 × 10−6
AEE (Δ kcal/min) --- 0.60 ± 0.05 1.12 ± 0.11 2 × 10−8 3 × 10−6 4 × 10−6
Energy exp. (kcal/3 h) 207 ± 11 315 ± 16 402 ± 24 2 × 10−8 4 × 10−6 8 × 10−6
Total AEE (Δ kcal/3 h) --- 108 ± 9 (+36 kcal/h) 201 ± 19 (+67 kcal/h) 2 × 10−8 3 × 10−6 4 × 10−6
RER (VCO2/VO2) 0.84 ± 0.02 0.88 ± 0.01 0.90 ± 0.02 0.019 0.003 0.112
Total carbohydrate oxidation (mg/min) 135 ± 18 276 ± 14 392 ± 25 1 × 10−6 4 × 10−6 0.0002
Δ mg/min above control --- 141 ± 16 253 ± 26 1 × 10−6 5 × 10−6 0.0002
Total in 3 h (g) 24.2 ± 3.2 49.7 ± 2.5 70.6 ± 4.6 1 × 10−6 4 × 10−6 0.0002
Δ above control (g) --- 25.5 ± 2.9 (2.1 fold) 45.5 ± 4.6 (2.9 fold) 1 × 10−6 5 × 10−6 0.0002
Soleus carbohydrate oxidation (Δ mg/min) --- 113 ± 13 202 ± 21 1 × 10−6 5 × 10−6 0.0002

Mean ± SEM. Metabolic rate and carbohydrate oxidation during the postprandial period following the ingestion of 75 g glucose. Each individual performed a sedentary control and one or both of the levels of local contractile activity. The delta (Δ) is the difference between sedentary control and activity. Differences between conditions were determined by a mixed effects model followed by Tukey’s multiple comparison tests. N = 15 for SPU1 effects and N = 10 for SPU2. See also Experiment II results in Figure S1 and Table S2.