Comparison 5. Subgroup analysis: stage CKD (HIF versus ESA).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
5.1 Proportion reaching target haemoglobin	14	4601	Risk Ratio (M‐H, Random, 95% CI)	1.00 [0.93, 1.07]
5.1.1 CKD	6	1369	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.90, 1.16]
5.1.2 HD	5	1150	Risk Ratio (M‐H, Random, 95% CI)	0.96 [0.88, 1.06]
5.1.3 HD and PD	3	2082	Risk Ratio (M‐H, Random, 95% CI)	0.99 [0.86, 1.15]
5.2 Thrombosis	11	17026	Risk Ratio (M‐H, Random, 95% CI)	1.09 [0.86, 1.39]
5.2.1 CKD	4	7959	Risk Ratio (M‐H, Random, 95% CI)	1.04 [0.59, 1.86]
5.2.2 HD	1	323	Risk Ratio (M‐H, Random, 95% CI)	0.99 [0.06, 15.75]
5.2.3 HD and PD	6	8744	Risk Ratio (M‐H, Random, 95% CI)	1.08 [0.81, 1.46]