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. 2022 Aug 10;11(8):1544. doi: 10.3390/antiox11081544

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Antioxidant enzymes correlate with response to therapy and survival in HGSOC patients. (A) Expression levels of SLC7A11 in HGSOC patients, grouped for their pathological response to platinum-based therapy (complete response vs. residual disease after completing the therapy). Statistical significance of differences in gene expression levels in responders (n = 432) and non-responders (n = 202) was evaluated by the Mann–Whitney test. (B,C) Kaplan–Meier estimates of survival obtained on the Kaplan—Meier plotter analyzing post-progression survival in HGSOC patients treated with platinum-based chemotherapy.