Table 3.
Pharmacotechnical [65] characterization of bioadhesive oral films (F-UBO and R).
| Pharmacotechnical Parameter * [66] | F-UBO | R |
|---|---|---|
| Weight uniformity (mg) | 63 ± 1.79 | 62 ± 3.27 |
| Thickness (mm) | 0.069 ± 0.006 | 0.065 ± 0.004 |
| Folding endurance value | >300 | >300 |
| Tensile strength (kg/mm2) | 2.17 ± 0.49 | 2.36 ± 0.98 |
| Elongation % | 56.33 ± 0.92 | 52.16 ± 1.22 |
| Moisture content % (w/w) | 8.11 ± 0.78 | 8.42 ± 0.69 |
| pH | 6.97 ± 0.01 | 7.02 ± 0.04 |
| Disintegration time (seconds) | 124 ± 3.67 | 127 ± 4.81 |
| Swelling rate (% after 6 h) | 195 ± 5.24 | 202 ± 5.68 |
| Ex vivo bioadhesion time (minutes) | 86 ± 4.12 | 91 ± 3.79 |
* Expressed as mean value ± SD; R—reference (films without UBO); F-UBO—UBO-loaded bioadhesive oral film; UBO—U. barbata extract in canola oil; SD—standard deviation.