Skip to main content
. 2022 Jul 27;11(8):1464. doi: 10.3390/antiox11081464

Figure 1.

Figure 1

Oxidative dysfunction in the heart due to Western diet, with decrease in antioxidant defences, causing mitochondrial dysfunction, leading to electrophysiological dysfunction with twist and sub-endocardialdysfunction. Exogenous antioxidants (HEART diet) improve antioxidative function with reduced Ca overloading and reversal of mitochondrial and electrophysiological dysfunction. (Modified from Reference [1], VanderPolA, Euro J Heart Failure 2019, under the license http://creativecommons.org/licenses/by-nc/4.0/, accessed on 15 June 2022).