Table 1.
a–g. Circadian parameters for whole-week recordings, weekdays and weekend days for wrist skin temperature (a), motor activity (b), time in movement (c), sleep probability (d) and total (e), circadian (f) and infrared (g) exposure.
a | ||||||||||||
Wrist Skin Temperature | ||||||||||||
Whole week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 12:53 ± 0:08 | 14:07 ± 0:12 | 4.57 | <0.0001 | 12:47 ± 0:09 | 13:51 ± 0:12 | 3.77 | 0.000 | 13:22 ± 0:09 | 14:25 ± 0:15 | 3.07 | 0.002 |
NPM | 2:45 ± 0:10 | 3:25 ± 0:10 | 3.88 | 0.000 | 2:52 ± 0:10 | 3:20 ± 0:11 | 2.58 | 0.010 | 2:58 ± 0:10 | 3:54 ± 0:15 | 3.10 | 0.002 |
V-day | 31.33 ± 0.04 | 31.18 ± 0.06 | −2.06 | 0.040 | 31.29 ± 0.04 | 31.10 ± 0.06 | −2.40 | 0.017 | 31.35 ± 0.04 | 31.28 ± 0.07 | −1.14 | 0.257 |
V-night | 33.88 ± 0.04 | 33.99 ± 0.07 | 1.58 | 0.115 | 33.92 ± 0.05 | 34.04 ± 0.07 | 1.68 | 0.094 | 34.01 ± 0.05 | 34.22 ± 0.06 | 2.67 | 0.008 |
RAN | 0.51 ± 0.01 | 0.56 ± 0.02 | 2.47 | 0.014 | 0.53 ± 0.01 | 0.59 ± 0.02 | 2.87 | 0.004 | 0.53 ± 0.01 | 0.59 ± 0.02 | 2.59 | 0.010 |
IS | 0.56 ± 0.01 | 0.57 ± 0.02 | 0.69 | 0.494 | 0.61 ± 0.01 | 0.63 ± 0.02 | 1.36 | 0.176 | 0.75 ± 0.01 | 0.75 ± 0.01 | 0.39 | 0.701 |
CFI | 0.65 ± 0.01 | 0.67 ± 0.01 | 1.52 | 0.129 | 0.67 ± 0.01 | 0.69 ± 0.01 | 2.19 | 0.030 | 0.72 ± 0.00 | 0.73 ± 0.01 | 1.64 | 0.102 |
CI | 0.59 ± 0.01 | 0.60 ± 0.02 | 0.57 | 0.568 | 0.56 ± 0.01 | 0.57 ± 0.02 | 0.28 | 0.781 | 0.48 ± 0.01 | 0.51 ± 0.02 | 1.34 | 0.182 |
b | ||||||||||||
Motor Activity | ||||||||||||
Whole week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 13:10 ± 0:04 | 13:39 ± 0:06 | 3.30 | 0.001 | 13:02 ± 0:04 | 13:26 ± 0:07 | 2.70 | 0.007 | 13:27 ± 0:04 | 14:07 ± 0:09 | 3.58 | <0.0001 |
NPM | 3:03 ± 0:04 | 3:12 ± 0:07 | 1.10 | 0.270 | 2:57 ± 0:05 | 3:07 ± 0:07 | 1.31 | 0.190 | 3:18 ± 0:05 | 3:18 ± 0:09 | −0.28 | 0.779 |
V-day | 19.39 ± 0.36 | 17.27 ± 0.45 | −2.95 | 0.003 | 19.60 ± 0.36 | 17.54 ± 0.46 | −2.94 | 0.004 | 19.43 ± 0.41 | 17.71 ± 0.48 | −1.72 | 0.086 |
V-night | 2.26 ± 0.04 | 1.98 ± 0.05 | −4.48 | <0.0001 | 2.22 ± 0.04 | 1.93 ± 0.05 | −4.56 | <0.0001 | 2.11 ± 0.04 | 1.84 ± 0.04 | −3.75 | <0.0001 |
RAN | 0.49 ± 0.01 | 0.44 ± 0.01 | −2.55 | 0.011 | 0.49 ± 0.01 | 0.45 ± 0.01 | −2.45 | 0.015 | 0.49 ± 0.01 | 0.45 ± 0.01 | −1.33 | 0.183 |
IS | 0.39 ± 0.00 | 0.37 ± 0.01 | −2.64 | 0.009 | 0.45 ± 0.01 | 0.44 ± 0.01 | −1.13 | 0.258 | 0.65 ± 0.01 | 0.64 ± 0.01 | −1.94 | 0.054 |
CFI | 0.67 ± 0.00 | 0.65 ± 0.01 | −2.59 | 0.010 | 0.69 ± 0.00 | 0.68 ± 0.01 | −1.92 | 0.056 | 0.76 ± 0.00 | 0.75 ± 0.01 | −1.39 | 0.166 |
CI | 0.59 ± 0.01 | 0.69 ± 0.01 | 6.74 | <0.0001 | 0.56 ± 0.01 | 0.64 ± 0.01 | 5.24 | <0.0001 | 0.49 ± 0.01 | 0.59 ± 0.01 | 6.07 | <0.0001 |
c | ||||||||||||
Time in Movement | ||||||||||||
Whole week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 13:16 ± 0:04 | 13:51 ± 0:07 | 3.91 | <0.0001 | 13:10 ± 0:04 | 13:43 ± 0:07 | 3.50 | <0.0001 | 13:33 ± 0:05 | 14:18 ± 0:09 | 3.82 | <0.0001 |
NPM | 3:06 ± 0:04 | 3:11 ± 0:07 | 0.91 | 0.365 | 2:54 ± 0:04 | 3:04 ± 0:07 | 0.87 | 0.387 | 3:14 ± 0:05 | 3:18 ± 0:08 | 0.28 | 0.779 |
V-day | 30.72 ± 0.35 | 30.65 ± 0.58 | 0.23 | 0.820 | 30.95 ± 0.35 | 30.89 ± 0.57 | 0.15 | 0.885 | 31.03 ± 0.39 | 31.54 ± 0.63 | 0.84 | 0.402 |
V-night | 1.48 ± 0.05 | 1.51 ± 0.09 | −0.46 | 0.647 | 1.43 ± 0.05 | 1.39 ± 0.08 | −0.51 | 0.613 | 1.22 ± 0.04 | 1.22 ± 0.07 | −0.22 | 0.825 |
RAN | 0.73 ± 0.01 | 0.73 ± 0.01 | 0.15 | 0.881 | 0.74 ± 0.01 | 0.73 ± 0.01 | 0.28 | 0.783 | 0.74 ± 0.01 | 0.75 ± 0.02 | 0.80 | 0.427 |
IS | 0.50 ± 0.01 | 0.48 ± 0.01 | −1.55 | 0.123 | 0.55 ± 0.01 | 0.55 ± 0.01 | −0.44 | 0.658 | 0.72 ± 0.01 | 0.70 ± 0.01 | −2.13 | 0.034 |
CFI | 0.76 ± 0.00 | 0.75 ± 0.01 | −1.14 | 0.255 | 0.78 ± 0.00 | 0.78 ± 0.01 | −0.51 | 0.611 | 0.84 ± 0.00 | 0.83 ± 0.00 | −1.59 | 0.113 |
CI | 0.66 ± 0.01 | 0.75 ± 0.01 | 6.38 | <0.0001 | 0.64 ± 0.01 | 0.71 ± 0.01 | 5.32 | <0.0001 | 0.58 ± 0.01 | 0.66 ± 0.01 | 5.26 | <0.0001 |
d | ||||||||||||
Sleep Probability | ||||||||||||
Whole Week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 14:16 ± 0:06 | 14:25 ± 0:09 | 0.95 | 0.344 | 13:58 ± 0:07 | 14:14 ± 0:09 | 1.45 | 0.147 | 13:52 ± 0:07 | 14:16 ± 0:10 | 2.53 | 0.012 |
NPM | 3:07 ± 0:04 | 3:18 ± 0:07 | 1.08 | 0.281 | 3:01 ± 0:05 | 3:11 ± 0:07 | 0.79 | 0.428 | 3:14 ± 0:05 | 3:22 ± 0:09 | 0.61 | 0.542 |
V-day | 0.06 ± 0.00 | 0.04 ± 0.01 | −4.40 | <0.0001 | 0.06 ± 0.00 | 0.04 ± 0.00 | −4.12 | <0.0001 | 0.06 ± 0.00 | 0.05 ± 0.01 | −3.13 | 0.002 |
V-night | 0.84 ± 0.00 | 0.86 ± 0.01 | 1.69 | 0.091 | 0.85 ± 0.01 | 0.86 ± 0.01 | 2.05 | 0.041 | 0.86 ± 0.00 | 0.87 ± 0.01 | 0.91 | 0.365 |
RAN | 0.78 ± 0.01 | 0.81 ± 0.01 | 3.41 | 0.001 | 0.79 ± 0.01 | 0.82 ± 0.01 | 4.03 | <0.0001 | 0.80 ± 0.01 | 0.82 ± 0.01 | 2.02 | 0.045 |
IS | 0.61 ± 0.01 | 0.62 ± 0.01 | 2.02 | 0.044 | 0.65 ± 0.01 | 0.67 ± 0.01 | 2.44 | 0.015 | 0.77 ± 0.01 | 0.77 ± 0.01 | 0.36 | 0.723 |
CFI | 0.74 ± 0.00 | 0.77 ± 0.01 | 3.88 | 0.000 | 0.76 ± 0.00 | 0.79 ± 0.01 | 4.09 | <.0001 | 0.80 ± 0.00 | 0.82 ± 0.01 | 2.58 | 0.010 |
CI | 0.70 ± 0.01 | 0.76 ± 0.01 | 5.02 | <0.0001 | 0.68 ± 0.01 | 0.74 ± 0.01 | 5.29 | <0.0001 | 0.60 ± 0.01 | 0.63 ± 0.01 | 1.42 | 0.157 |
e | ||||||||||||
Total Light Exposure | ||||||||||||
Whole Week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 13:14 ± 0:03 | 13:27 ± 0:05 | 2.76 | 0.006 | 13:10 ± 0:04 | 13:24 ± 0:06 | 2.63 | 0.009 | 13:24 ± 0:04 | 13:46 ± 0:06 | 3.25 | 0.001 |
NPM | 2:42 ± 0:04 | 2:51 ± 0:07 | 0.71 | 0.480 | 2:28 ± 0:04 | 2:37 ± 0:07 | 0.45 | 0.656 | 2:32 ± 0:05 | 2:39 ± 0:08 | 0.60 | 0.548 |
V-day | 1.41 ± 0.03 | 1.64 ± 0.04 | 4.09 | <0.0001 | 1.42 ± 0.03 | 1.66 ± 0.04 | 4.27 | <0.0001 | 1.42 ± 0.03 | 1.66 ± 0.05 | 3.71 | <0.0001 |
V-night | 0.01 ± 0.00 | 0.01 ± 0.00 | −0.09 | 0.932 | 0.01 ± 0.00 | 0.01 ± 0.00 | −0.74 | 0.458 | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.32 | 0.751 |
RAN | 0.47 ± 0.01 | 0.54 ± 0.01 | 3.99 | <0.0001 | 0.47 ± 0.01 | 0.55 ± 0.01 | 4.20 | <0.0001 | 0.47 ± 0.01 | 0.55 ± 0.02 | 3.65 | <0.0001 |
IS | 0.55 ± 0.01 | 0.60 ± 0.01 | 3.17 | 0.002 | 0.60 ± 0.01 | 0.65 ± 0.01 | 3.55 | <0.0001 | 0.75 ± 0.01 | 0.76 ± 0.01 | 1.50 | 0.134 |
CFI | 0.83 ± 0.00 | 0.84 ± 0.00 | 3.08 | 0.002 | 0.85 ± 0.00 | 0.86 ± 0.00 | 3.62 | <0.0001 | 0.89 ± 0.00 | 0.90 ± 0.00 | 1.82 | 0.070 |
CI | 0.72 ± 0.01 | 0.79 ± 0.01 | 4.75 | <0.0001 | 0.70 ± 0.01 | 0.76 ± 0.01 | 4.22 | <0.0001 | 0.63 ± 0.01 | 0.71 ± 0.01 | 4.58 | <0.0001 |
f | ||||||||||||
Blue Light Exposure | ||||||||||||
Whole week | Weekdays | Weekend | ||||||||||
Western spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 13:08 ± 0:03 | 13:21 ± 0:05 | 2.46 | 0.014 | 13:06 ± 0:03 | 13:17 ± 0:05 | 1.90 | 0.058 | 13:17 ± 0:04 | 13:41 ± 0:06 | 3.40 | 0.001 |
NPM | 2:36 ± 0:04 | 2:46 ± 0:07 | 0.76 | 0.448 | 2:19 ± 0:05 | 2:37 ± 0:08 | 1.36 | 0.176 | 2:27 ± 0:06 | 2:30 ± 0:09 | 0.17 | 0.862 |
V-day | 1.05 ± 0.03 | 1.30 ± 0.04 | 4.92 | <0.0001 | 1.05 ± 0.03 | 1.31 ± 0.04 | 5.04 | <0.0001 | 1.06 ± 0.03 | 1.32 ± 0.05 | 4.24 | <0.0001 |
V-night | 0.00 ± 0.00 | 0.01 ± 0.00 | 0.31 | 0.754 | 0.00 ± 0.00 | 0.01 ± 0.00 | 1.02 | 0.307 | 0.00 ± 0.00 | 0.00 ± 0.00 | −0.25 | 0.800 |
RAN | 0.35 ± 0.01 | 0.43 ± 0.01 | 4.92 | <0.0001 | 0.35 ± 0.01 | 0.44 ± 0.01 | 4.99 | <0.0001 | 0.35 ± 0.01 | 0.44 ± 0.02 | 4.24 | <0.0001 |
IS | 0.51 ± 0.01 | 0.56 ± 0.01 | 4.25 | <0.0001 | 0.56 ± 0.01 | 0.62 ± 0.01 | 4.40 | <0.0001 | 0.72 ± 0.01 | 0.74 ± 0.01 | 1.99 | 0.047 |
CFI | 0.81 ± 0.00 | 0.83 ± 0.00 | 4.28 | <0.0001 | 0.83 ± 0.00 | 0.85 ± 0.00 | 4.78 | <0.0001 | 0.88 ± 0.00 | 0.89 ± 0.00 | 2.38 | 0.018 |
CI | 0.70 ± 0.01 | 0.77 ± 0.01 | 4.97 | <0.0001 | 0.67 ± 0.01 | 0.74 ± 0.01 | 4.41 | <0.0001 | 0.60 ± 0.01 | 0.68 ± 0.01 | 4.86 | <0.0001 |
g | ||||||||||||
Infrared Exposure | ||||||||||||
Whole Week | Weekdays | Weekend | ||||||||||
Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | Western Spain | Portugal | Z | Pr | |
DPM | 13:03 ± 0:03 | 13:10 ± 0:05 | 1.47 | 0.144 | 13:01 ± 0:03 | 13:09 ± 0:06 | 1.65 | 0.099 | 13:17 ± 0:04 | 13:30 ± 0:04 | 2.71 | 0.007 |
NPM | 2:42 ± 0:05 | 2:53 ± 0:07 | 0.94 | 0.349 | 2:30 ± 0:05 | 2:43 ± 0:08 | 0.64 | 0.526 | 2:36 ± 0:05 | 2:37 ± 0:09 | −0.13 | 0.899 |
V-day | 186.00 ± 12.00 | 242.00 ± 20.00 | 3.59 | <0.0001 | 179.00 ± 12.00 | 238.00 ± 21.00 | 3.63 | <0.0001 | 214.00 ± 17.00 | 267.00 ± 26.00 | 3.03 | 0.003 |
V-night | 0.06 ± 0.01 | 0.05 ± 0.01 | −0.32 | 0.752 | 0.06 ± 0.01 | 0.05 ± 0.01 | −0.51 | 0.608 | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.17 | 0.868 |
RAN | 1.00 ± 0.00 | 1.00 ± 0.00 | 0.67 | 0.502 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.17 | 0.242 | 0.99 ± 0.00 | 1.00 ± 0.00 | 0.91 | 0.360 |
IS | 0.20 ± 0.00 | 0.21 ± 0.01 | 2.38 | 0.018 | 0.28 ± 0.01 | 0.30 ± 0.01 | 1.77 | 0.077 | 0.54 ± 0.01 | 0.56 ± 0.01 | 0.95 | 0.341 |
CFI | 0.63 ± 0.00 | 0.64 ± 0.00 | 2.00 | 0.046 | 0.66 ± 0.00 | 0.67 ± 0.00 | 2.35 | 0.019 | 0.74 ± 0.00 | 0.76 ± 0.01 | 1.47 | 0.142 |
CI | 0.38 ± 0.01 | 0.45 ± 0.01 | 5.12 | <0.0001 | 0.35 ± 0.01 | 0.41 ± 0.01 | 4.20 | <0.0001 | 0.31 ± 0.01 | 0.34 ± 0.01 | 2.88 | 0.004 |
DPM (h): Day Phase Marker = M10: the mid-point timing for the 10 consecutive hours with the highest values for motor activity, time in movement, TAPL and light exposure; L10: the mid-point timing for the 10 consecutive hours with the lowest values for wrist skin temperature and sleep; NPM (h): night phase marker; M5: the mid-point time of the 5 consecutive hours with the highest values for wrist skin temperature and sleep; L5: the mid-point time of the 5 consecutive hours with the lowest values for motor activity, time in movement, TAPL and light exposure; V-day = M10 mean value for motor activity (g/30 s), time in movement (s/30 s), TAPL (arbitrary units, A.U.) and light exposure (log10lux) and L10 mean value for wrist skin temperature and sleep; V-night = M5 mean values for wrist skin temperature and sleep; L5 mean value for motor activity, time in movement, TAPL and light exposure; RA: relative amplitude (A.U.); IS: interdaily stability (A.U.); CFI: Circadian Function Index (A.U.); CI: circadianity index (A.U.). Statistics: Mann–Whitney U test. Significance level: Pr < 0.002 (Bonferroni corrected). See Methods and Supplementary Information for further details.