Figure 4.

Genetic environment of bla_OXA-58 genes in 29 A. baumannii isolates from dogs and cats. (A–D) bla_OXA-58 located on different plasmids. Extent and orientation of genes and open reading frames (orf) are shown by a horizontal arrow with the gene names below. The bla_OXA-58 gene is shown in red, araC1 in yellow, lysE in blue, orfs in grey and other genes in light green. Insertion sequence (IS) elements are represented by a black framed box with the orientation of the transposase genes shown within. Primer pairs used for bridging PCRs are shown as numbers (forward primer in black, reverse primer in red) above the respective genes (Supplementary Materials Table S3). Numbers to the right indicate the size of the genetic regions displayed in the figure and the estimated total size of the plasmids (shown in brackets).