Table 1.

Factors of antibiotic elution for particular consideration during clinical application and their issues.

Factors for Particular Consideration	Issue
(1) Choice of cement	Cement brand and type
(2) Geometry of the cement body	Volume and surface area of the cement
(3) Porosity of the cured cement	Use of a vacuum system, homogenization of antibiotic to the cement powder, porogens in the cement
(4) Antibiotic and antibiotic combinations	Choice of antibiotic, proportion in the cement, combinations