Table A2.

Commercially available double loaded bone cements; MRSA: methicillin-resistant Staphylococcus aureus; MRSE: methicillin-resistant Staphylococcus epidermidis adapted from Kuhn et al. 2017 [6].

Antibiotic Groups	Antibiotics	Activity against	Cement Example
Aminoglycoside and Lincosamide	Gentamicin and Clindamycin	Many gram-positive and—negative bacteria (Staphylococcus species, Enterococcus species, Pseudomonas, Escherichia coli, Klebsiella, Proteus	Copal® G+C
Aminoglycoside and Glycopeptide	Gentamicin and Vancomycin	Many gram-positive bacteria (Staphylococcus species, MRSA, MRSE, Enterococcus species	Copal® G+V
Macrolide and Polymyxin	Erythromycin and Colistin	Gram-positive bacteria (Streptococcus species, Staphylococcus species), anaerobic bacteria (Corynebacteria)	Simplex® with Erythromycin/Colistin