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Exposure to MC-LR significantly reduces Glutathione-S-transferase (GST) activity. GST activity was significantly reduced in CDHFD mice exposed to MC-LR but was restored on treatment with targeted antioxidant therapy using pNaKtide or NAC. Treatment of CDHFD mice with antioxidant alone did not alter the enzyme activity. * p ≤ 0.05, *** p ≤ 0.001.
