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. 2022 Jul 27;11(8):1466. doi: 10.3390/antiox11081466

Figure 2.

Figure 2

Treatment with HXT down-regulates PLpro mRNA expression and reduces apoptosis in epithelial cells. (A) PLpro mRNA expression in Calu-3, Caco-2 and HepG2 cells before and after treatment with 10 μM HXT for 24 h. (B) Percentage of apoptosis measured by FITC Annexin V in pCMV3 Calu-3, Caco-2 and HepG2 cells, and in PLpro cells treated or not with 10 µM HXT for 24 h. Values are plotted as mean ± SD of three independent experiments repeated at least in duplicate. Data were analyzed by 2-tailed t-tests, * p < 0.05, ** p < 0.01, *** p < 0.001 vs. pCMV3; § p < 0.05, §§ p < 0.01 vs. PLpro.