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. 2022 Aug 11;13:931280. doi: 10.3389/fpsyt.2022.931280

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Copyright © 2022 Kazmi, Wallen, Yang, Alkhatib, Schwandt, Feng, Gao, Diazgranados, Ramchandani and Barb.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bivariate plot of cytokine MCP1 and co-occurring symptoms in AUD. MCP-1 (y-axis) vs. (A) Sleep measured by PSQI (x-axis, R = 0.40, p = 0.004), (B) Anxiety measured by BSA (x-axis, R = 0.39, p = 0.006), (C) Depression measured by MADRS (x-axis, R = 0.44, p = 0.002), (D) Number of drinking days (x-axis, R = 0.42, p = 0.002), (E) Average drinks per day (x-axis, R = 0.51, p < 0.001), (F) Heavy drinking days (x-axis, R = 0.54, p < 0.001), and (G) Total number of drinks (x-axis, R = 0.61, p < 0.001). Red line represents regression line.