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. 2022 Aug 11;13:931280. doi: 10.3389/fpsyt.2022.931280

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Copyright © 2022 Kazmi, Wallen, Yang, Alkhatib, Schwandt, Feng, Gao, Diazgranados, Ramchandani and Barb.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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One-way plot of IL-8, and MCP-1 vs. co-occurring dichotomized symptoms in AUD. X-axis indicates 3 dichotomized symptoms in individuals with AUD who reported having good sleep and those who reported having poor sleep (first panel), individuals with AUD who currently have a mood disorder compared to those who currently do not have a mood disorder (2nd panel), individuals with AUD who currently have an anxiety Disorder compared to those who currently do not have an anxiety disorder (3rd panel). Y-axis is cytokine levels of: (A) IL-8 (p = 0.02, p = 0.003, p = 0.04 respectively for sleep, mood and anxiety), (B) MCP-1 levels (p = 0.05, p = 0.01, p = 0.01 respectively for sleep, mood and anxiety).