Table 3.
Significant cytokine associations with age, sleep, anxiety, depression and drinking (AUD group).
| Drinking (TLFB) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cytokines | Age |
Sleep (PSQI) |
Anxiety (BSA) |
Depression (MADRS) |
Avg drinks per day | Heavy drink days | No of drink days | Total drinks |
| IL-8 | −0.08 | 0.49* | 0.45* | 0.48* | 0.41* | 0.21 | 0.17 | 0.39* |
| IL-10 | −0.05 | 0.33 | 0.51* | 0.58** | 0.45* | 0.26 | −0.12 | 0.41 |
| MCP-1 | 0.54*** | 0.40** | 0.39** | 0.44** | 0.51*** | 0.54**** | 0.42** | 0.61**** |
| TNF-a | 0.21 | 0.24 | 0.16 | 0.25 | 0.29 | 0.43* | 0.50** | 0.46* |
| IL-23 | 0.50* | 0.11 | 0.11 | 0.22 | 0.34 | 0.38 | 0.30 | 0.40 |
Numerical values represent Spearman Correlation Coefficient. Asterisk indicates significance level (The *, **, ***, and **** symbols indicate the value of P < 0.05, P < 0.01, P < 0.001, and P < 0.0001 respectively).