Table 4.

Direct reprogramming protocols

Pink cells indicate positive inducers (growth factors, sera, small molecules); yellow cells indicate inhibitors; green cells indicate media and additional supplements used; gray cells indicate selection steps; orange cells indicate measurements. Acronyms: AHCF, adult human CFs; AHDF, adult human dermal fibroblasts; CF, CFs; H9F, H9-derived fibroblasts; HFF, neonatal human foreskin fibroblasts; HLF, human fetal lung fibroblasts; MEF, mouse embryonic fibroblasts; TTF, TTFs; 2ME, ß-mercaptoethanol; FBS, fetal bovine serum; FGF2, basic fibroblast growth factor; FGF10, fibroblast growth factor 10; Glutamax, l-alanyl-l-glutamine; ITS, insulin, transferrin, selenium supplement; KSR, KnockOut Serum Replacement; LIF, leukemia inhibitory factor; NEAA, non-essential amino acids supplement; VEGFA, vascular endothelial growth factor.