Table 3.
All-Cause in-Hospital Mortality n = 140 (44%) |
14-Day Mortality n = 37 (12%) |
28-Day Mortality n = 41 (13%) |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. | % | p | OR | CI | No. | % | p | OR | CI | No. | % | p | OR | CI | |
Blood sample | 12 | 8.6% | 0.288 | 1.60 | 0.67–3.83 | 4 | 10.8% | 0.317 | 1.79 | 0.57–5.61 | 6 | 14.6% | 0.042 | 2.83 | 1.04–7.71 |
Patient-related device sample | 2 | 1.4% | 0.207 | 0.36 | 0.07–1.76 | 0 | 0.0% | * | * | * | 1 | 2.4% | 0.880 | 0.85 | 0.10–6.98 |
Respiratory sample | 82 | 58.6% | 0.000 | 2.85 | 1.81–4.50 | 19 | 51.4% | 0.356 | 1.38 | 0.70–2.74 | 20 | 48.8% | 0.531 | 1.23 | 0.64–2.38 |
Skin & soft tissue sample | 41 | 29.3% | 0.211 | 0.74 | 0.46–1.19 | 14 | 37.8% | 0.509 | 1.27 | 0.63–2.58 | 14 | 34.1% | 0.870 | 1.06 | 0.53–2.12 |
Urine sample | 3 | 2.1% | 0.000 | 0.08 | 0.02–0.26 | 0 | 0.0% | * | * | * | 0 | 0.0% | * | * | * |
Infection with MDRAB | 127 | 90.7% | 0.000 | 3.43 | 1.77–6.63 | 29 | 78.4% | 0.627 | 0.81 | 0.35–1.88 | 37 | 90.2% | 0.125 | 2.31 | 0.79–6.76 |
Infection with sensitive AB | 13 | 9.3% | 0.29 | 0.15–0.56 | 8 | 21.6% | 1.23 | 0.53–2.85 | 4 | 9.8% | 0.43 | 0.15–1.26 | |||
Hospital-acquired infection | 93 | 66.4% | 0.027 | 1.68 | 1.06–2.65 | 9 | 24.3% | 0.000 | 0.18 | 0.08–0.40 | 29 | 70.7% | 0.120 | 1.76 | 0.86–3.59 |
Community-acquired infection | 47 | 33.6% | 0.60 | 0.38–0.94 | 28 | 75.7% | 5.55 | 2.52–12.22 | 12 | 29.3% | 0.57 | 0.28–1.16 | |||
90-day recurrence of infection | 10 | 7.1% | 0.082 | 0.50 | 0.23–1.09 | 0 | 0.0% | * | * | * | 0 | 0.0% | * | * | * |
H/O exposure to Gram-negative | 29 | 20.7% | 0.951 | 0.98 | 0.57–1.69 | 13 | 35.1% | 0.026 | 2.31 | 1.10–4.82 | 9 | 22.0% | 0.856 | 1.08 | 0.49–2.38 |
Any H/O exposure to infection | 33 | 23.6% | 0.704 | 0.91 | 0.54–1.51 | 14 | 37.8% | 0.050 | 2.05 | 1.00–4.21 | 10 | 24.4% | 0.972 | 0.99 | 0.46–2.12 |
H/O exposure to K. pneumoniae | 8 | 5.7% | 0.295 | 0.63 | 0.26–1.51 | 4 | 10.8% | 0.416 | 1.60 | 0.52–4.97 | 4 | 9.8% | 0.554 | 1.41 | 0.46–4.34 |
H/O exposure to P. aeruginosa | 14 | 10.0% | 0.723 | 1.15 | 0.54–2.44 | 7 | 18.9% | 0.039 | 2.65 | 1.05–6.69 | 5 | 12.2% | 0.504 | 1.42 | 0.51–3.94 |
H/O exposure to E. coli | 13 | 9.3% | 0.282 | 1.58 | 0.69–3.65 | 6 | 16.2% | 0.039 | 2.86 | 1.06–7.74 | 3 | 7.3% | 0.967 | 0.97 | 0.28–3.42 |
H/O exposure to Gram-positive | 15 | 10.7% | 0.950 | 1.02 | 0.50–2.09 | 6 | 16.2% | 0.243 | 1.77 | 0.68–4.61 | 6 | 14.6% | 0.371 | 1.54 | 0.60–3.99 |
H/O exposure to MRSA | 4 | 2.9% | 0.468 | 0.64 | 0.19–2.16 | 2 | 5.4% | 0.573 | 1.57 | 0.33–7.44 | 1 | 2.4% | 0.642 | 0.61 | 0.08–4.86 |
H/O exposure to MSSA | 4 | 2.9% | 0.468 | 0.64 | 0.19–2.16 | 0 | 0.0% | * | * | * | 3 | 7.3% | 0.209 | 2.38 | 0.62–9.17 |
Polymicrobial infection | 118 | 84.3% | 0.000 | 2.66 | 1.53–4.61 | 21 | 56.8% | 0.010 | 0.40 | 0.20–0.81 | 35 | 85.4% | 0.093 | 2.17 | 0.88–5.37 |
Concurrent infection with Gram-negative | 107 | 76.4% | 0.000 | 2.57 | 1.58–4.18 | 16 | 43.2% | 0.005 | 0.37 | 0.18–0.73 | 30 | 73.2% | 0.232 | 1.56 | 0.75–3.25 |
Concurrent infection K. pneumoniae | 70 | 50.0% | 0.001 | 2.18 | 1.38–3.43 | 6 | 16.2% | 0.004 | 0.26 | 0.11–0.64 | 20 | 48.8% | 0.199 | 1.54 | 0.80–2.97 |
Concurrent infection P. aeruginosa | 64 | 45.7% | 0.022 | 1.70 | 1.08–2.67 | 9 | 24.3% | 0.062 | 0.47 | 0.21–1.04 | 12 | 29.3% | 0.190 | 0.621 | 0.30–1.27 |
Concurrent infection E. coli | 29 | 20.7% | 0.343 | 1.32 | 0.75–2.32 | 4 | 10.8% | 0.214 | 0.50 | 0.17–1.48 | 7 | 17.1% | 0.817 | 0.903 | 0.38–2.15 |
Concurrent infection with Gram-positive | 69 | 49.3% | 0.016 | 1.73 | 1.11–2.72 | 11 | 29.7% | 0.119 | 0.55 | 0.26–1.16 | 17 | 41.5% | 0.969 | 0.99 | 0.51–1.92 |
Concurrent infection MRSA | 20 | 14.3% | 0.791 | 1.09 | 0.58–2.07 | 2 | 5.4% | 0.136 | 0.33 | 0.08–1.42 | 6 | 14.6% | 0.853 | 1.09 | 0.43–2.77 |
Concurrent infection MSSA | 8 | 5.7% | 0.060 | 1.31 | 0.48–3.58 | 3 | 8.1% | 0.360 | 1.84 | 0.50–6.78 | 1 | 2.4% | 0.435 | 0.44 | 0.06–3.44 |
Antibiotic-related ADE | 86 | 61.4% | 0.000 | 3.13 | 1.98–4.96 | 16 | 43.2% | 0.741 | 0.89 | 0.45–1.78 | 24 | 58.5% | 0.082 | 1.80 | 0.93–3.50 |
No.: number, p: probability value, OR: odds ratio, CI: confidence interval, IQR: intra-quartile range, ID: infectious disease, LOS: length of stay, H/O: history of, MDRAB: multi-drug resistant A. baumannii, AB: A. baumannii, MRSA: methicillin-resistant Staphylococcus aureus, MSSA: Methicillin-sensitive Staphylococcus aureus, ADE: adverse drug event, *: value cannot be produced by the software.