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. 2022 Jul 30;10(8):1843. doi: 10.3390/biomedicines10081843

Table 1.

Rate and equilibrium constants of proteins binding to PD–L1.

Antibody Ka 1/Ms Kd 1/s KD M R2−
Anti-PD-L1 mAb 1.82 × 105 4.48 × 10−6 2.469 × 10−11 0.9834
IAB 9.50 × 104 1.80 × 10−4 1.894 × 10−9 0.9786
Pro1 8.40 × 104 1.0 × 10−7 <1.0 × 10−12 0.9683
Pro2 7.52 × 104 2.85 × 10−7 3.794 × 10−12 0.9861
Pro3 7.21 × 104 3.05 × 10−7 4.229 × 10−12 0.9863