Figure 7.

Schematic representation and RNAseq reads coverage of FGFR2-LGSN fusion transcript identified in OC11 sample: (A) fusion partner gene structures upstream and downstream of fusion site; (B) LGSN exon coverage by normalized RNA sequencing reads in OC-11 sample (blue) and in control ovarian cancer samples without fusion (orange). Double normalized exon coverage by RNA sequencing reads is shown: (i) by exon length and (ii) by overall gene expression level in a sample. *—the coverage of exon in OC-11 sample is higher than the 95th percentile of exon coverage in unrelated control ovarian cancer samples without fusion.