| ACE2 | angiotensin-converting enzyme 2 |
| AD | Alzheimer’s disease |
| AIH | autoimmune hepatitis |
| AILI | APAP-induced liver injury |
| ALD | alcoholic liver disease |
| ALT | alanine aminotransferase |
| AMPK | adenosine 5‘-monophosphate (AMP)-activated protein kinase |
| Ang II | angiotensin II |
| APAP | acetaminophen |
| APP/PS1 | amyloid precursor protein plus presenilin-1 |
| ARE | antioxidant response element |
| ASH | alcoholic steatohepatitis |
| AST | aspartate aminotransferase |
| ATP | adenosine triphosphate |
| Aβ | β-amyloid |
| BACE | β-site amyloid-precursor-cleaving enzyme |
| BMDCs | bone-marrow-derived dendritic cells |
| CAT | catalase |
| cGMP | cyclic guanosine 3′, 5′-monophosphate |
| CIA | collagen-induced arthritis |
| CNS | central nervous system |
| COVID-19 | Coronavirus Disease 2019 |
| COX-2 | Cyclooxygenase-2 |
| Cul3 | CULLIN3 |
| CYP 450 | cytochrome P450 |
| CYP2E1 | cytochrome P450 2E1 |
| DAPI | 4′,6-diamidino-2-phenylindole |
| DFT | density functional theory |
| DILI | drug-induced liver injury |
| DMF | Dimethyl fumarate |
| DPPH | 2,2-diphenyl-1-picrylhydrazyl |
| dTHP-1 | Human THP-1 cells differentiated to the macrophage phenotype |
| EC | Epieatechin |
| ECG | Epieatechin gallate |
| EGC | Epigalloeatechin |
| EGCG | (−)-epigallocatechin-3-gallate |
| FDA | Food and Drug Administration |
| GCL | glutamate cysteine ligase |
| GSH-Px | glutathione peroxidase |
| GST | glutathione-S-transferases |
| IC50 | half maximal inhibitory concentration |
| IDMF | di-(methyl fumarate) |
| IFN-I | I interferons |
| IL-17 | interleukin-17 |
| IL-1β | interleukin 1 beta |
| IL-6 | interleukin 6 |
| iNOS | inducible nitric oxide synthase |
| GCLC | catalytic subunit of glutamate–cysteine ligase |
| GCLM | gutamate-cysteine ligase modifier subunitl |
| GSH | glutathione |
| GSK-3 | glycogen synthase kinase 3 |
| HAS | hydroxy-α-sanshool |
| HBV | hepatitis B |
| HBx | hepatitis B x protein |
| HCC | hepatocellular carcinoma |
| HCV | hepatitis C |
| HFD | high-fat diet |
| HMOX-1 | heme-oxigenase-1 |
| HO-1 | heme-oxigenase-1heme-oxigenase-1 |
| HSC | hepatic stellate cell ICC intrahepatic cholangiocarcinoma |
| Keap1 | Kelch-like ECH-associated protein 1 |
| LN | lupus nephritis |
| LPS | Lipopolysaccharide |
| LSEC | liver sinusoidal endothelial cell |
| MAF | musculoaponeurotic fibrosarcoma |
| MAO | Monoamine oxidase |
| MS | multiple sclerosis |
| NAFLD | non-alcoholic fatty liver disease |
| NAPQI | N-acetyl-1,4-benzoquinone imine |
| NDP52 | nuclear dot protein 52 |
| NF-κB | nuclear factor kappa B |
| NLR | nucleotide-binding domain leucine-rich repeat-related |
| NLRP3 | nucleotide-binding domain leucine-rich repeat-related (NLR) family pyrin do-main-containing 3 |
| NOX | NADPH-oxidase |
| NQO1 | NAD (P) H-quinone oxidoreductase 1 |
| Nrf2 | nuclear factor E2-related factor 2 |
| NS3 | nonstructural protein 3 |
| NS5A | nonstructural protein 5A |
| OSI | oxidative stress index |
| PBC | primary biliary cholangitis PSC primary sclerosing cholangitis |
| PD | Parkinson’s disease |
| PTEN | phosphatase and tensin homolog |
| PINK | phosphatase and tensin homolog (PTEN)-induced kinase |
| PSC | primary sclerosing cholangitis |
| qPCR | Quantitative Real-time PCR |
| RNA | Ribonucleic Acid |
| RA | Rheumatoid arthritis |
| ROS | reactive oxygen species |
| SARS-CoV-2 | severe acute respiratory syndrome coronavirus 2 |
| SFN | Sulforaphane |
| SLE | systemic lupus erythematosus |
| Socs3 | suppresses cytokine signaling 3 |
| SOD | superoxide dismutase |
| STAT3 | Signal transducer and activator of transcription 3 |
| TAS | total antioxidant status |
| Th17 | T helper type 17 |
| TLR7 | Toll-like receptor 7 |
| TLR9 | Toll-like receptor 9 |
| TMPRSS2 | transmembrane protease serine 2 |
| TNF-α | tumor necrosis factor alpha |
| TrX-1 | thioredoxin-1 |
| TRX | thioredoxin |
| TrxR1 | thioredoxin reductase 1 |
| TOS | total oxidant status |
| UDCA | ursodeoxycholic acid |
| α-syn | α-synuclein |
| γ-GCS | γ-glutamyl cysteine synthetase |