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. 2022 Aug 19;11(8):1608. doi: 10.3390/antiox11081608

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Parameters related to NO metabolism in the placenta and kidney. (A,B) NO relative concentrations estimated in placental and renal cortex homogenates. (C,D) eNOS gene expressions and (E,F) mRNA (upper charts) and protein (lower charts) expressions of arginase isoforms 1 and 2 in the placenta and kidney, respectively. The quantitative fold changes in gene expressions were determined relative to the corresponding values for the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) housekeeping gene. Values are expressed as mean ± SEM of at least six animals per group: ** p < 0.01, *** p < 0.001 vs. NP. NP: normal pregnant rats; PE-11: preeclamptic rats at GD11; PE-19: preeclamptic rats at GD19.