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Effect of ARNI and ivabradine on the serum level of aldosterone (A) and the aldosterone/angiotensin II ratio (AA2 ratio) (B) in SHRs after six weeks of treatment. ARNI, sacubitril/valsartan; C, Wistar controls; IVA, ivabradine; SHRs, spontaneously hypertensive rats. Results are presented as means ± SEM. n = 6 per group. One-way, two-tailed ANOVA followed by multiple comparisons with a Bonferroni post-hoc test; # p < 0.05 vs. SHR.
