m6A |
N6-methyladenosine |
TBI |
Traumatic brain injury |
BGA |
Brain-gut axis |
IBD |
Inflammatory bowel disease |
CNS |
Central nervous system |
ENS |
Enteric nervous system |
ANS |
Autonomic nervous system |
HPA |
Hypothalamus-pituitary-adrenal |
TNF-α |
Tumour necrosis factor-alpha |
IL-1β/6/1/8/17 |
Interleukin-1 beta/6/1/8/17 |
BBB |
Blood–brain barrier |
TJs |
Tight junctions |
PD |
Parkinson’s disease |
AD |
Alzheimer’s disease |
ALS |
Amyotrophic lateral sclerosis |
MS |
Multiple sclerosis |
BCAAs |
Branched chain amino acids |
LPS |
Lipopolysaccharides |
BFLPS |
Bacteroides fragilis lipopolysaccharides |
iNOS |
Inducible nitric oxide synthase |
p-tau |
Phosphorylated tau |
NFκB |
Nuclear factor kappaB |
COX-2 |
Cyclooxygenase-2 |
CCR9+
|
C-C chemokine receptor type 9+
|
IFNγ |
Interferon-γ |
c-Maf |
C-musculoaponeurotic-fibrosarcoma |
RORγt |
Retinoic acid-related orphan receptor gamma t |
SPMS |
Secondary progression multiple sclerosis |
ZO |
Zonula occludens |
VE-cadherin |
Vascular endothelial–cadherin |
JAM-1 |
Junction adhesion molecule-1 |
GCs |
Glucocorticoids |
ICAM-1 |
Intracellular adhesion molecule-1 |
IEC |
Intestinal epithelial cell |
SAE |
Sepsis-associated encephalopathy |
YTHDF1/2/3 |
YTH domain family 1/2/3 |
WT |
Wild type |
GAPDH |
Glyceraldehyde-3-phosphate dehydrogenase |
METTL3/14/16/5 |
Methyltransferase-like 3/14/16/5 |
WTAP |
Wilms’tumor 1-associating protein |
SAM |
S-adenosylmethionine |
NLSs |
Nuclear localisation signals |
ZC3H13 |
Zinc finger CCCH-type containing 13 |
MTC |
Methyltransferase cpmplex |
RBM15 |
RNA binding motif protein 15 |
ZCCHC4 |
Zinc finger CCHC domain containing 4 |
MACOM |
m6A-METTL Associated Complex |
RNA POL II |
RNA polymerase II |
ZFD1/2 |
Zinc finger domain1/2 |
RRM |
RNA recognition motif |
SPOC domain |
SpenParalog and OrthologsC-terminal domain |
ssRNA |
Single-stranded RNA |
snRNA |
Small nuclear RNA |
lncRNA |
Long non-coding RNA, |
CPSF5/6 |
Cleavage and polyadenylation specific factor 5/6 |
FTO |
Fat mass and obesity-associated protein |
ALKBH5 |
AlkB homolog 5 |
m6Am |
N6, 2′-O-dimethyladenosine |
M1A |
N1-methyladenosine |
YTHDC1/2 |
YTH domain containing 1/2 |
HNRNPA2B1 |
Heterogenous nuclear ribonucleoprotein A2B1 |
HNRNPC |
Heterogenous nuclear ribonucleoprotein C |
hn-RNPG |
Heterogenous nuclear ribonucleoprotein G |
EIF3 |
Eukaryotic initiation factor 3 |
IGF2BP1/2/3 |
Insulin-like growth factor 2 mRNA-binding protein 1/2/3 |
hm6A |
N6-hydroxymethyladenosine |
f6A |
N6-formyladenosine |
A |
Adenosine |
DCP2 |
Decapping RNA2 |
dCasRx-M3 |
Dead RfxCas13d-Methyltransferase-like 3 |
dCasRx-A5 |
Dead RfxCas13d-AlkB homolog 5 |
SRSF3/10 |
Serine/arginine-rich splicing Factor 3/10 |
MCM4/5/2 |
Minichromosome maintenance deficient 4/5/2 |
AML |
Acute myeloid leukaemia |
HIF-1α |
Hypoxia-inducible factor 1α |
Dgcr8 |
DiGeorge syndrome critical region gene 8 |
3′/5′UTR |
3′/5′untranslated region |
G3BP1/2 |
Ras GTPase-activating protein-binding protein 1/2 |
Dapk1 |
Death Associated Protein Kinase 1 |
Fadd |
Fas-associated death domain |
Ngfr |
Nerve growth factor receptor |
mESC |
Mouse embryonic stem cell |
SYP |
Synaptophysin |
CXCL2 |
C-X-C motif chemokine ligand 2 |
IFN-CD4 |
Interferon-CD4 |
GRIN1/2A |
Glutamate receptor, ionotropic,N-methyl D-aspartate 1/2A |
GRIA1 |
Glutamate Receptor AMPA Type Subunit 1 |
CAMK2A/2B |
Calcium/Calmodulin Dependent Protein Kinase 2A/2B |
NSPCs |
Neural stem/progenitor cells |
Apc |
Adenomatous polyposis coli |
PTEN |
Phosphatase and tensin homolog deleted on chromosome ten |
OGD |
Oxygen-glucose deprivation |
HNSCC |
Head and neck squamous cell carcinoma |
CBP |
CREB binding proteins |
SOCSS |
Suppressors of cytokine signaling |
H/R |
Hypoxia/reoxygenation |
MCAO/R |
Middle cerebral arteryocclusion/reperfusion |
OGD/R |
Oxygen-glucose deprivation/reoxygenation |
CCI |
Controlled cortical impact |
6-OHDA |
6-hydroxydop amine |
SCFAs |
Short-chain fatty acids |
MERIP-Seq |
Methylated RNA immunoprecipitation sequencing |
GF |
Germ free |
SPF |
Specific pathogen free |
NSPs |
Nonstarch polysaccharides |
ILC3 |
Innate lymphoid cells |
Nr4a1 |
Nuclear receptor subfamily 4 group A member1 |
TRAF6 |
Tumour necrosis factor receptor-associated factor 6 |
DDX60 |
DEXD/H box helicase 60 |
XPO1 |
Exportin 1 |
TCGA |
The Cancer Genome Atlas |
COAD |
Colonic adenocarcinoma |
NMDA |
N-methyl-D-aspartate |
ROS |
Reactive oxygen stke |
NLRP3 |
Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing-3 |
p75NTR |
P75-neurotrophin receptor |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
TINCR |
Non-protein coding RNA |
GSDMD |
Gasdermin D |
HO-1 |
Heme oxygenase-1 |
MMPs/2/9 |
matrix metalloproteinases/2/9 |
Keap1 |
Kelch-like ECH-associated protein 1 |
ARE |
Antioxidant response element |