Skip to main content
. 2022 Jul 31;11(8):1151. doi: 10.3390/biology11081151

Table 1.

Gene targets significantly associated with the 21 miRNA markers candidates for the in silico analysis.

miRNA-Target Enrichment Results
Gene p-Value FDR O
Rt		 Interacting
miRs		 miR 1 miR 2 mioR 3 miR 4 miR 5 miR 6 miR 7 miR 8
PTEN 2.75 × 10−6 0.011 0.126 8 miR-26a miR-29b miR-23a miR-92a miR-155 miR-34a miR-486 miR-21
ATP1A1 3.02 × 10−5 0.016 0.048 4 miR-93 miR-92a miR-26a miR-155
CIT 4.20 × 10−5 0.016 0.052 4 miR-93 miR-29b miR-92a miR-486
GATA3 1.59 × 10−5 0.016 0.018 3 miR-92a miR-29b miR-27a
GIT2 3.70 × 10−5 0.016 0.024 3 miR-26a miR-210 miR-92a
MYC 2.84 × 10−5 0.016 0.140 7 miR-26a miR-30a miR-92a miR-23a miR-125a miR-34a miR-29b
PPP1R2 4.20 × 10−5 0.016 0.052 4 miR-210 miR-142 miR-30a miR-34a
RGS5 3.13 × 10−5 0.016 0.079 5 miR-142 miR-92a miR-124 miR-9 miR-23a
STAT3 2.64 × 10−5 0.016 0.107 6 miR-92a miR-874 miR-21 miR-23a miR-124 miR-29b
TKT 3.70 × 10−5 0.016 0.024 3 miR-92a miR-26a miR-206
CAMKV 6.57 × 10−5 0.020 0.058 4 miR-92a miR-26a miR-23a miR-874
CCL8 6.22 × 10−5 0.020 0.008 2 miR-23a miR-92a
PDS5B 6.22 × 10−5 0.020 0.008 2 miR-27a miR-92a
CTC1 7.08 × 10−5 0.020 0.127 6 miR-93 miR-92a miR-26a miR-29b miR-181a miR-874
COL4A2 9.55 × 10−5 0.024 0.032 3 miR-29b miR-92a miR-210
HES1 9.55 × 10−5 0.024 0.032 3 miR-23a miR-92a miR-9
CPEB4 1.07 × 10−4 0.025 0.101 5 miR-26a miR-34a miR-92a miR-874 miR-27a
KIAA1671 1.25 × 10−4 0.026 0.068 4 miR-93 miR-29b miR-92a miR-30a
LDHB 1.23 × 10−4 0.026 0.0350 3 miR-186 miR-23a miR-210
CNOT1 1.94 × 10−4 0.029 0.040 3 miR-93 miR-92a miR-23a
CSAG1 1.85 × 10−4 0.029 0.012 2 miR-186 miR-93
ESR1 2.04 × 10−4 0.029 0.116 5 miR-206 miR-29b miR-26a miR-142 miR-874
FUK 1.85 × 10−4 0.029 0.012 2 miR-93 miR-92a
MCM3 1.56 × 10−4 0.029 0.037 3 miR-93 miR-92a miR-210
P2RX7 2.15 × 10−4 0.029 0.078 4 miR-9 miR-146a miR-186 miR-125a
PFDN2 1.56 × 10−4 0.029 0.037 3 miR-93 miR-210 miR-92a
PIK3CG 2.15 × 10−4 0.029 0.078 4 miR-29b miR-27a miR-142 miR-26a
PSMC3 1.85 × 10−4 0.029 0.01 2 miR-92a miR-23a
WDR77 1.94 × 10−4 0.029 0.076 4 miR-27a miR-93 miR-186 miR-125a
PPARD 2.38 × 10−4 0.031 0.043 3 miR-92a miR-29b miR-30a
KCTD5 2.89 × 10−4 0.036 0.084 4 miR-92a miR-26a miR-125a miR-34a
TET2 2.87 × 10−4 0.036 0.045 3 miR-92a miR-29b miR-26a
APC 3.43 × 10−4 0.037 0.048 3 miR-210 miR-27a miR-142
CPEB2 3.47 × 10−4 0.037 0.088 4 miR-210 miR-26a miR-92a miR-142
FAU 3.69 × 10−4 0.037 0.016 2 miR-92a miR-23a
GPD1L 3.69 × 10−4 0.037 0.016 2 miR-210 miR-142
IRAK1 3.43 × 10−4 0.037 0.048 3 miR-93 miR-92a miR-142
PHB 3.69 × 10−4 0.037 0.016 2 miR-27a miR-26a
SCAF8 3.69 × 10−4 0.037 0.016 2 miR-29b miR-92a
VMAC 3.43 × 10−4 0.037 0.048 3 miR-146a miR-186 miR-125a
HMGCR 4.05 × 10−4 0.039 0.051 3 miR-92a miR-29b miR-27a
HECTD1 4.74 × 10−4 0.043 0.053 3 miR-210 miR-142 miR-92a
TBC1D16 4.74 × 10−4 0.043 0.053 3 miR-26a miR-186 miR-210
TUT1 4.74 × 10−4 0.043 0.053 3 miR-93 miR-92a miR-26a
ABCB9 6.12 × 10−4 0.046 0.020 2 miR-210 miR-26a
CDH1 6.34 × 10−4 0.046 0.059 3 miR-92a miR-23a miR-9
DUSP5 5.51 × 10−4 0.046 0.056 3 miR-27a miR-92a miR-26a
IL6 6.34 × 10−4 0.046 0.059 3 miR-142 miR-26a miR-125a
INPP5A 6.12 × 10−4 0.046 0.020 2 miR-210 miR-142
KIF20A 6.12 × 10−4 0.046 0.020 2 miR-92a miR-23a
NEK6 6.12 × 10−4 0.046 0.020 2 miR-92a miR-23a
PDE4B 6.12 × 10−4 0.046 0.020 2 miR-26a miR-34a
SOCS6 6.34 × 10−4 0.046 0.059 3 miR-23a miR-27a miR-142
UBE2R2 6.12 × 10−4 0.046 0.020 2 miR-93 miR-92a
ZNF618 6.34 × 10−4 0.046 0.059 3 miR-21 miR-27a miR-210

Significance was considered under a level of FDR < 0.05, and a minimum number of 2 interactions gene-miRNAs. In italics are indicated the 10 top-ranked targets (p < 4.5 × 10−5). FDR: False Discovery Rate; OR: Odd ratio.