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. 2022 Aug 13;11(8):1568. doi: 10.3390/antiox11081568

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The influences of geraniol (100 and 200 mg/kg) administration for 14 days prior to renal ischemia/perfusion (I/R) induced injury on the renal inflammatory mediators (a) TNF-α, (b) IFN-γ, (c) MCP-1, and (d) IL-10, and on apoptosis including gene (mRNA) expression of (e) Bax, (f) Bcl-2 and (g) Caspase 3, and (h) Caspase 9. All values are expressed as mean ± SD. ¥ indicates statistically significant from the sham group, ₳ indicates statistically significant from the renal I/R group, and φ indicates statistically significant from renal I/R + geraniol 100 mg/kg group (p < 0.05) using one-way ANOVA followed by Tukey’s post hoc test.