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. 2022 Jul 28;10(8):1811. doi: 10.3390/biomedicines10081811

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of chronic CBD treatment on the kindling scores induced by pentylenetetrazole in rats. The development of kindling was characterized by the following parameters: (a) mortality rate due to generalized seizures, (b) the total number of PTZ injections to reach the kindled state, (c) the number of generalized seizures, and (d) the latency to the first generalized seizure. Data are expressed as mean ± SEM in the bar graph and as mean (solid line) with the range in the floating bar graphs; * p < 0.05 vs. control.