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Lack of long-term effect of CBD (60 mg/kg) in the PTZ-kindling model. (a) Latency to maximal seizure observed after PTZ injection. (b) Duration of the generalized seizures (clonic convulsion with loss of righting reflex and/or bouncing, two or more clonic convulsions, tonic convulsion or status epilepticus) induced by a challenge dose of PTZ. Data are expressed as mean ± SEM (n = 7–11) for each parameter.
