Table 3.
Deregulated lncRNAs in psoriasis in keratinocytes. In this table, miRNAs, which are targets of lncRNAs that function as decoys, are highlighted in bold.
| Author, Year | Non-Coding RNA | Expression | Target Genes (Indirect Targets) | Cell Type |
|---|---|---|---|---|
| Liu et al., 2021 [139] | CDR1as | Down | (EGR3, GATA6, GATA3, FOXN3) | HEKs |
| Liu et al., 2021 [139] | hsa_skin_088763 | Down | (GATA6, SIK2, IL17RD, EGR3, FAS, LRIG1, PPARGC1A) | HEKs |
| Jia et al., 2019 [135] | MEG3 | Down | miR-21 | HaCaT |
| Liu et al., 2021 [139] | hsa_skin_05227 | Down | GATA6 | HEKs |
| Yazıcı et al., 2021 [140] | 7SL-RNA | Down | - | HEKs |
| Moldovan et al., 2020 [141] | circEXOC6B | Down | - | HEKs |
| Moldovan et al., 2020 [142] | circSLC8A | Down | - | HEKs |
| Moldovan et al., 2020 [142] | circRHOBTB | Down | - | HEKs |
| Qiao et al., 2018 [136] | MSX2P1 | Up | miR-6731, (S100A7) | HaCaT, NHEK |
| Gao et al., 2018 [142] | MIR31HG | Up | - | HaCaT |
| Li et al., 2017 [143] | lncRNA-H19 | Up | miR-130b, (DSG1) | HEKs |
| Szegedi et al., 2010 [144] | PRINS | Up | - | HeLa |
| Cai et al., 2019 [145] | PRANCR | Up | - | HEKs |
| Moldovan et al., 2020 [141] | cTNFRSF21, | Up | - | HEKs |
| Moldovan et al., 2020 [141] | circDOCK1 | Up | - | HEKs |
| Moldovan et al., 2020 [141] | circARAP2 | Up | - | HEKs |
| Moldovan et al., 2020 [141] | circDDX21 | Up | - | HEKs |
| Moldovan et al., 2020 [141] | circZRANB1 | Up | - | HEKs |
Abbreviations: circRNA, circular RNA; lncRNA, long non-coding RNA; HEKs, human embryonic kidney cell line; HaCaT, human epidermal keratinocyte cell line; NHEK, normal human epidermal keratinocyte.