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. 2022 Aug 14;12(8):641. doi: 10.3390/bios12080641

Table 1.

Comparison of gold derivative-based glucose biosensors.

Modified Working Electrode * LOD (mmol L−1)/Sensitivity (μA mM−1 cm−2) Linear Determination Range (mmol L−1) Transduction System/Mediator Reference
GOx/PDDA-rGO/MnO2/AuNPs/GC 0.0018/83.7 0.015–0.845 CV/K4[Fe(CN)6] [9]
GOx/PANI/Au nanorods/Pt 0.0058/13.8 0.0176–1.00 CPA/– [25]
GOx/DGNs/screen-printed 0.007/46.76 0.028–8.40 CV/K4[Fe(CN)6] [19]
GOx/graphene/nano-Au/GC 0.017/56.93 0.2–2.00 Sweep voltammetry/– [18]
GOx/rGO/β-lactoglobulin/DGNs/GC 0.0229/46.2 0.05–6.00 ChA/K4[Fe(CN)6] [8]
GOx/HRP/carbon ink 0.03/– 0.05–1.00 ChA/K4[Fe(CN)6] [12]
GOx/DGNs/GR 0.059/169 0.10–9.97 CPA/PMS [44]
GOx/PANI-AuNPs(6nm)-GOx/GR 0.070/65.4 0.10–16.5 CPA/PMS [48]
GOx/Ppy-AuNPs(6nm)-GOx/GR 0.071/55.4
Ppy/GOx/AuNPs(el depos.)/GR 0.20/21.7 1.00–19.9 CPA/PMS [23]
Chitosan-AuNPs nanocomposite/GC 0.370/– 0.40–10.7 CV/– [13]
RBCM/PQQ/GDH/Au 1.06/– 2.50–10.0 ChA/– [17]
This work
Ppy/GOx/DGNs/GR 0.070/59.4 0.10–19.9 CPA/PMS
PANI/GOx/DGNs/GR 0.18/43.9 0.30–19.9 CPA/PMS

* GC—glassy carbon, GDH—quinoprotein glucose dehydrogenase, HRP—horseradish peroxidase, MnO2—manganese dioxide, PDDA—poly(diallyldimethylammonium chloride), PQQ—pyrroloquinoline, rGO—reduced graphene oxide, RBCM—red blood cell membrane.