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. 2022 Aug 19;10(8):2018. doi: 10.3390/biomedicines10082018

Figure 4.

Figure 4

Expression of the components of the chemerin system in different tissues, on the left showing the mRNA expression data for each in normalized transcripts per million (nTPM), and on the right, where available, the score is the protein expression data based on immunohistochemical data manually scored with regard to staining intensity (negative, weak, moderate or strong) and fraction of stained cells (<25%, 25–75% or >75%). Each combination of intensity and fractions is automatically converted into a protein expression level score as follows: negative—not detected; weak <25%—not detected; weak combined with either 25–75% or 75%—low; moderate <25%—low; moderate combined with either 25–75% or 75%—medium; strong <25%—medium, strong combined with either 25–75% or 75%—high. In addition to this, protein expression values are manually adjusted as necessary when evaluated by our expert annotators. (a) chemerin (RARRES2), (b) CCRL2, (c) chem1 (CMKLR1) and (d) chem2 (GPR1). Data from the Human Protein Atlas v21.1 [60] (https://www.proteinatlas.org/ENSG00000106538-RARRES2/tissue, https://www.proteinatlas.org/ENSG00000174600-CMKLR1/tissue, https://www.proteinatlas.org/ENSG00000121797-CCRL2/tissue and https://www.proteinatlas.org/ENSG00000183671-GPR1/tissue accessed on 11 August 2022).