Figure 5.

Arc associates with H3K9Ac-S10P. Image of a neuronal nucleus obtained using STORM. Cultured hippocampal neurons were treated with 4BF for 4 h, fixed and stained for Arc and H3K9Ac-S10P, which marks sites undergoing active transcription. (A) Arrowheads point to close appositions between Arc and the histone mark (scale bar = 1 µm). (B) Enlarged sections showing the association in greater detail. Arrows inside the Arc puncta point to what appear to be invasions of H 3K9Acc-S10P into Arc puncta (scale bar 200 nm). Regions of overlap appear in yellow.