Table 4.
Univariable and multivariable logistic regression analysis of selected predictors of malignancy (benign/cancer; 0/1) in patients with AUS/FLUS thyroid tumor diagnosis.
| Independent Variables | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|
| OR (±95% CI) | p-Value | OR (±95% CI) | p-Value | |
| Sex: for female | 0.36 (0.18–0.73) | <0.004 * | 2.36 (0.08–67.95) | 0.615 |
| Age: for <55 years old | 3.38 (1.62–7.08) | 0.001 * | 108.9 (0.99–1189.62) | 0.049 * |
| Microcalcifications | 20.33 (9.67–42.76) | <0.0001 * | 164.92 (2.62–1034.68) | 0.015 * |
| Hypoechoic | 27.92 (9.67–80.56) | <0.0001 * | 250.97 (1.50–4186.21) | 0.034 * |
| Irregular margin | 34.49 (10.38–114.56) | <0.0001 * | 12.69 (0.92–173.56) | 0.056 |
| Taller than wide | 27.51 (10.43–72.51) | <0.0001 * | 921.44 (2.36–3587.85) | 0.024 * |
| High vascularity | 4.15 (2.17–7.93) | <0.0001 * | 19.46 (0.43–872.59) | 0.124 |
| TSH for ≥2.5mUI/L | 40.26 (17.60–92.08) | <0.0001 * | 168.69 (4.56–6237.33) | 0.005 * |
*—statistically significant; OR—odds ratio; 95%CI—95% confidence interval.