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. 2022 Aug 10;14(16):3861. doi: 10.3390/cancers14163861

Table 2.

The list of miRNAs and lncRNAs and their target mRNAs involved in the pathogenesis and characteristics of somatotroph tumors.

miRNA Expression Target Genes (Putative)
miR-15a, miR-16-1 down regulated GHR, IGF-1, IGF1R, IGF2R
miR-34b, miR-326, miR-432, miR-548c-3p, miR-570, miR-603 down regulated HMGA1, HMGA2, E2F1,
miR-128 down regulated BMI1
miR-23b, down regulated HMGA2
miR-130b down regulated CCNA2
miR-185 up/down regulated SSTR2
miR-338-3p, miR-423-5p up regulated Pttg1
miR-107 up regulated AIP
miR-26b up regulated PTEN
miR-184 up regulated IGF1R
miR-21-5p up regulated PDCD4 and Smad7
lncRNA Expression Target
H19 down regulated 4E-BP1
up regulated not determined
MEG3 up regulated not determined