Table 1.
Recent studies on ZIF–8–based nanoplatforms for biomedical imaging.
| Nanocomposites | Applications | Properties | Ref. |
|---|---|---|---|
| LA–AuNR/ZIF–8 | CT | high X–ray absorption coefficient (Au) | [14] |
| DOX–Pt–tipped Au@ZIF–8 | CT | high X–ray absorption coefficient (Pt, Au)/good photothermal conversion efficiency (Pt, Au) | [25] |
| Mn–ZIF–8/5–Fu | MRI | enhanced relaxation (Mn) | [28] |
| BSA–MnO2/Ce6@ZIF–8 | MRI | enhanced relaxation (Mn) | [33] |
| Fe3O4–ZIF–8 | MRI | responsive T2–T1 switching MRI contrast agent (Fe3O4) | [26] |
| Mn3O4@PAA@ZIF–8 | MRI | enhanced relaxation (Mn) | [20] |
| ZIF–8/DMPP | MRI/PAI | enhanced relaxation (Mn)/strong NIR absorption (PDA) | [31] |
| ZIF–8/DOX–PD–FA | MRI/FI | enhanced relaxation (Si–Gd NPs)/fluorescence optical imaging ability (Si–Gd NPs) | [15] |
| Gd/Tm–PB@ZIF–8/PDA | MRI/FI | enhanced relaxation (Gd/Tm–PB)/fluorescence optical imaging ability (Gd/Tm–PB) | [27] |
| Mn–Zn–ZIF–PEG | MRI/FI | enhanced relaxation (Mn)/fluorescence optical imaging ability (2–methylimidazolate) | [29] |
| Fe3O4@PAA/AuNCs/ZIF–8 | MRI/FI/CT | enhanced relaxation (Fe3O4)/fluorescence optical imaging ability (Au)/high X–ray absorption coefficient (Au) | [23] |
| Au@ZIF–8 | PAI | strong NIR absorption (Au) | [30] |
| ZCNs | PAI | strong NIR absorption (carbon nanomaterials) | [21] |
| PDAs–ZIF–8 | PAI/IR | excellent photothermal–converted acoustic wave signals (PDA)/good photothermal conversion efficiency (PDA) | [22] |
| Au@MOF | PAI/IR | excellent photothermal–converted acoustic wave signals (Au)/good photothermal conversion efficiency (Au) | [32] |
Abbreviations: LA, lactobionic acid; CT, computed tomography; DOX, doxorubicin; MRI, magnetic resonance imaging; BSA, bovine serum albumin; Ce6, chlorin e6; PAA, polyacrylic acid; DMPP, DOX, Mn2+, polydopamine, and polyethylene glycol; PAI, photoacoustic imaging; FA, folic acid; FI, fluorescence imaging; PB, Prussian blue; PDA, polydopamine; PEG, polyethylene glycol; ZCNs, ZIF–8 derived carbon nanoparticles; IR, imaging infrared.