3-UTR	3′-untranslational region
25-HC	25-hydroxycholesterol
α-KG	α-ketoglutaric acid
ABC	ATP-binding cassette
ABCA1	ATP-binding cassette subfamily A member 1
ACAT	acyl-CoA: cholesterol acyltransferase
ACC	acetyl-CoA carboxylases
ACLY	ATP-citrate lyase
ACSL	long-chain acyl-CoA synthetase
ACSS2	acetyl-CoA synthetase 2
AICAR	5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
AKT	protein kinase B
AMPK	AMP-activated protein kinase
ASCT2	alanine/serine/cysteine-preferring transporter 2
ATGL	adipose triglyceride lipase
BBB	blood–brain barrier
COPII	coat protein complex II
CPT1	carnitine palmitoyltransferase 1
CE	cholesteryl esters
CESD	cholesterol storage disease
DGAT1	diacylglycerol acyltransferase 1
EGFR	epidermal growth factor receptor
EMT	epithelial–mesenchymal transition
ER	endoplasmic reticulum
ESCC	esophageal squamous cell carcinoma
FAs	fatty acids
FAO	fatty acid oxidation
FASN	fatty acid synthase
FDPS	farnesyldiphosphate synthase
FIT	fat-storage-inducing transmembrane
GBM	glioblastoma
GLS	glutaminase
Gluts	glucose transporters
HBP	hexosamine biosynthesis pathway
HCC	hepatocellular carcinoma
HMGCS	hydroxymethylglutaryl-CoA synthase
HMGCR	hydroxymethylglutaryl-CoA reductase
HILPDA	hypoxia-inducible lipid droplet associated
Insig	insulin-inducible gene protein
IDH	isocitrate dehydrogenase
LDs	lipid droplets
LDL	low-density lipoprotein
LDLR	LDL receptor
IDOL	inducible degrader of LDLR
LPC	lysophosphatidylcholine
LPCATs	lysophosphatidylcholine acyltransferases
LXR	liver X receptor
MBOAT	membrane-bound O-acyltransferase
MCTs	monocarboxylate transporters
NASH	non-alcoholic steatohepatitis
NLSD	neutral lipid storage disease
OAA	oxaloacetate
PD1	programmed cell death protein 1
PDH	pyruvate dehydrogenase
PD-L1	programmed death-ligand 1
PI3K	phosphoinositide 3-kinases
PLs	phospholipids
PLA	phospholipase A
ROS	reactive oxygen species
S1P	site 1 protease
S2P	site 2 protease
SCAP	SREBP-cleavage activating protein
SCD1	stearoyl-CoA desaturase 1
SLC25A1	tricarboxylate transport protein, mitochondrial
SOAT1	sterol-O-acyltransferase 1
SQLE	squalene monooxygenase
SRE	sterol regulatory element
SREBF1	sterol regulatory element binding transcription factor 1
SREBP	sterol regulatory element-binding protein
TAG	triacylglycerol
TCA cycle	tricarboxylic acid cycle
TCGA	the cancer genome atlas
TKI	tyrosine kinase inhibitors
TMZ	temozolomide
VEGF	vascular endothelial growth factor