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. 2022 Aug 4;12(8):1075. doi: 10.3390/biom12081075

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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LC-MS/MS analysis of purine DNA lesions. (A) The levels (lesions/10⁶ nucleosides) of cPu and 8-oxo-Pu in the brain tissue of control SCID and tumor-bearing SCID mice; for specific values see Tables S3 and S4. (B) The levels (lesions/10⁶ nucleosides) of cPu and 8-oxo-Pu in the brain tissue of normal Swiss mice; for specific values see Tables S3 and S4. (C) The 5′R/5′S ratio of cdG and cdA in control SCID, tumor-bearing SCID, and normal Swiss mice; for specific values see Tables S5 and S6. The values are given as mean ± SD (n = 6); * (p < 0.05).