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. 2022 Aug 7;12(8):1086. doi: 10.3390/biom12081086

Table 1.

MTHFR SNP combinations in our male hypo-fertile population (percentage of the total male population).

SNP Combination Number
(% of the Population)
Number, (%) of the
Patients w Hcy >15 µM)
C677C/A1298A (WT) 278(13.1%) 24 (8.6%)
T677T/A1298A 278(13.1%) 159 (57.8%)
C677T/A1298A 502(23.5%) 56 (11.2%)
C677T/A1298C 454 (21.4%) 86 (18.8%)
C677C/C1298C 186(8.7%) 22 (11.8%)
C677C/A1298C 422(19.7%) 40 (9.5%)
C677T/C1298C 4(0.2%) -
T667T/A1298C 3 (0.2%) 1
Total 2127 (100%) 388 (18.2%)