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Effect of guanylyl nucleotide on dopamine (A) and 5a (B) competition for [3H]-spiperone binding to D3 receptors present in a human cell membrane preparation. The assays were performed in the presence of 5 mM MgCl2 and 1.5 mM CaCl2 (black) or the presence of 154 mM NaCl and 1 mM GTP (blue).
