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. 2022 Aug 10;14(16):3859. doi: 10.3390/cancers14163859

Table 3.

Multivariate analysis of radiomic factors using the Cox proportional hazards regression model with the stepwise method.

Factor Hazard Ratio Lower 95%CI Upper 95%CI p Value Coefficient
OS
90 Percentile_HHH 0.5197 0.3223 0.8381 0.007267 −0.6545
LargeAreaEmphasis_LHH 1.7990 1.1260 2.8750 0.014120 0.5871
Mean_HHH 1.9730 1.2240 3.1790 0.005255 0.6795
Median_HLL 1.9840 1.2400 3.1740 0.004262 0.6852
LRFS
InverseVariance_HLL 3.5450 1.64500 7.638 0.0012310 1.2655
SmallDependenceHighGrayLevelEmphasis_HHH 0.2133 0.09202 0.4942 0.0003138 −1.5453
PFS
SmallDependenceHighGrayLevelEmphasis_HHH 0.3715 0.2065 0.6686 0.0009571 −0.9901
TotalEnergy_HHL 2.4610 1.3910 4.3550 0.0019840 0.9006
JointEntropy_HLL 0.4969 0.2943 0.8388 0.0088420 −0.6994

OS―overall survival; LRFS―local relapse-free survival; PFS―progression-free survival.