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. 2022 Aug 13;14(16):3915. doi: 10.3390/cancers14163915

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overexpression of FAM107A promotes prostate cancer cell cycle arrest and induces apoptosis in prostate cancer cells. (A) Detection of the effect of FAM107A on the cycle of DU 145 and PC 3 cells using flow cytometry. (B) Western blotting to verify changes in cyclin D1 and apoptosis markers Bax, Cleaved caspase-3, and Bcl-2. (C) Detection of apoptosis rate of both groups of cells using flow cytometry. (D,E) Quantitative analysis of cell cycle changes and changes in apoptosis rates. Data are expressed as the mean ± standard deviation of at least three experiments. *** for p < 0.001.